| Post Name | Assistant Professor in Paediatrics - Medical Education |
|---|---|
| Question Paper Code | 031/2024/OL |
| Category Code | 348/2023 |
| Date of Test | 23 March 2024 |
| Exam Type | Online Examination |
| Total Questions | 100 |
1
During embryogenesis, which of the following cells do not differentiate from neuro ectoderm
Answer
D. Microglia
2
Which of the following statements regarding growth and hormonal control of a child are true ? i. Foetal growth depends mainly on insulin and insulin-like growth factors ii. Infant growth according to Infant Child Puberty Model (ICP) is mainly by growth hormone iii. Child growth depends mainly on nutrition and environment iv. Pubertal growth depends on sex hormone
Answer
A. Statement i and iv are correct
3
Correct statement regarding Bone Age (BA) assessment is
Answer
D. Gilsanz-Ratib atlas is a digital atlas and is easy to interpret
4
Of the statements on pathogenesis of obesity, which one is false ?
Answer
A. Hormone leptin is synthesised from hypothalamus and increased in obesity
5
Which of the following statements regarding dyslexia is/are correct ? i. Dyslexia is the most common specific learning disability. ii. Males are more commonly affected than females. iii. Functional MRI findings in dyslexia are : anterior Broca's area is normal while two posterior areas, word analysis and word forming areas, are abnormal. iv. In dyslexic children there is developmental uncoupling between reading IQ (Intelligence Quotient) and true IQ.
Answer
C. i, iii, iv are correct
6
Which of the following statements regarding growth charts is correct ?
Answer
D. In growth charts-3 SD corresponds 0.13 percentile
7
Which of the following statements regarding adolescents with mental health problems is false ?
Answer
Question Cancelled
8
The most common test for assessing Intelligence Quotient (IQ) after three years
Answer
B. Wechsler's intelligence scale for children
9
With regards to development of a child, which of the following statements are correct ? i. Child attains object permanence by 9 months. ii. The mature sleep pattern in EEG is attained usually by 4-6 months. iii. Child can count four pennies correctly by 5 years. iv. Child can identify four primary colours correctly by three years.
Answer
A. Statements i and ii are correct
10
Which of the following sleep disorders is a predominant Rapid Eye Movement (REM) sleep event ?
Answer
A. Nightmare
11
Regarding fatty acid composition in the diet, which of the following statements is false ?
Answer
B. The optimum ratio of omega 3 is omega 6 fatty acid in the diet should be 10:1
12
Which of the parameters is not included in Global Hunger Index ?
Answer
B. Oedema
13
Which of the following statements regarding rickets is correct ? i. 1, 25-dihydroxycholecalciferol is elevated in type II vitamin D dependent rickets. ii. The earliest sign of clinical rickets is widening of wrists. iii. For the prevention of rickets, it is essential to have sunlight exposure with wavelength of 280-320 nm. iv. FGF 23 is a humoral mediator that increases proximal tubular reabsorption of phosphorus.
Answer
C. i, ii and iii are correct
14
Which of the following statements regarding fluid electrolyte balance is not correct ?
Answer
D. Atrial natriuretic peptide increases sodium reabsorption in medullary collecting system
15
Which statement is wrong with regards to SIADH ?
Answer
D. Urinary sodium is less than 30 mEq/L with corresponding serum sodium less than 135 mEq/L
16
4 year old boy presented with history of Diabetic ketoacidosis with serum sodium 126 mEq/L, serum potassium 2.4 mEq/L and pH 6.34 and serum bicarbonate 4 mEq/L. Child was treated with insulin infusion and fluid management. Child developed seizure and deterioration of sensorium with confusion on day 2. Clinical examination showed spastic quadriparesis. What is the most common diagnosis ?
Answer
A. Central pontine myelinolysis
17
Which is not a feature of Gordon's syndrome ?
Answer
C. It is also called Pseudo-hypoaldosteronism Type 1
18
Mechanism of action of Orlistat
Answer
C. Pancreatic lipase inhibitor
19
Gold standard investigation for diagnosis of acute appendicitis in a child
Answer
D. CT scan abdomen
20
GI endoscopy showing multiple aphthous ulcers with normal background in small intestine is characteristically seen in which condition ?
Answer
C. Crohn's disease
21
SGOT more than SGPT is seen in all of the following conditions except
Answer
D. Paracetamol toxicity
22
Alpha feto protein is elevated in all of the following conditions except
Answer
A. Reye's syndrome
23
What is the gene mutation associated with Watson-Alagille syndrome ?
Answer
A. JAG 1 mutation
24
Which statement regarding neonatal hemochromatosis is wrong ?
Answer
A. Marked elevation of SGOT and SGPT are present till late in diseases
25
In which of the following conditions Serum Albumin to Ascitic Albumin Gradient (SAG) is >1.1 ?
Answer
Question Cancelled
26
All are features of single gene disorder except
Answer
C. They will not have variable expressivity
27
Genetic testing is interpreted by all the factors except
Answer
B. Analytical utility
28
Choose the correct statement about Achondroplasia
Answer
C. Is an example of Gain of function variant type of inheritance
29
Which of the following illustration is wrong ?
Answer
Question Cancelled
30
A child is brought to you with visual defect and a diagnosis of Retinitis Pigmentosa is confirmed. Both parents have normal vision. This is an example for
Answer
D. Digenetic inheritance
31
The peculiar odor of urine in Tyrosinemia-type-1 is
Answer
A. Rancid butter
32
Which of the following deficiency can present as acquired hypertyrosinemia ?
Answer
C. Vitamin C
33
Intravenous Arginine infusion is benefitted in all the following except
Answer
D. Arginase deficiency
34
The main circulating form of Pyridoxine is
Answer
A. Pyridoxal 5' phosphate
35
All are true about Canavan disease except
Answer
D. Defective gene is located on Chromosome 18
36
Which of the following statement is false ?
Answer
B. Amniotic fluid volume increases at a steady rate up to 40 weeks
37
Choose the incorrect statement.
Answer
B. Variable deceleration occur with umbilical cord compression are slow in onset and resolution and will occur with uterine contractions
38
A fetus is subjected for Ultrasonographic evaluation. You are requested to give expert opinion based on the USG Report. Choose the wrong advice.
Answer
Question Cancelled
39
Which of the following statement is false ?
Answer
D. Twin to twin transfusion syndrome is more common in dizygotic twins
40
A five year old boy is brought to you with Hemiparesis, seizures and cognitive delay. There is history of birth asphyxia. The most likely area of injury in the newborn period is likely to be
Answer
C. Focal ischemic necrosis
41
Which is the correct sequence in the development of heart involving the following structures ? 1. Formation of septum primum. 2. Muscular ventricular septum. 3. A-V Valves. 4. Osteum secundum.
Answer
A. 1-2-3-4
42
Total fetal cardiac output is approximately
Answer
B. 450 ml/kg/min.
43
All the statements are true except
Answer
D. Children less than 4 years will have R:S ratio less than 1 in V4R
44
Which of the following statement is true ?
Answer
C. Presence of Left atrial and left ventricular volume overload indicates that the Qp:Qs is greater than 2:1
45
Pathologic ECHO findings in Rheumatic Mitral regurgitation include all the following except
Answer
B. Peak velocity is more than 2mt/sec
46
Select the true statement.
Answer
D. Arrythmogenic right ventricular cardiomyopathy is characterized by islands of fatty replacement and fibrosis
47
All are false statements about Milrinone except
Answer
A. Mechanism of action is inhibition of phosphodiesterase
48
Choose the wrong match.
Answer
B. Noonan syndrome-Osteosarcoma
49
All the following are indication for performing Micturating cystourethrography in children with UTI as per ISPN consensus guidelines except
Answer
B. E. Coli UTI in Infancy
50
A neonate presents with clinical features of failure to thrive, hypokalemia and metabolic alkalosis. The baby also has transient hyperkalemia and nephrocalcinosis. Which of the following genetic defect is the child most likely to have ?
Answer
C. KCNJ1
51
Which of the following is the most common cause of atypical Hemolytic uremic syndrome in Indian children and adolescents ?
Answer
A. Anti-factor H antibodies
52
2-year-old male child was followed up in pediatric neurology OPD from 6 months of age for myoclonic seizures and progressed to develop ataxia, dysarthria, sensorimotor neuropathy. The child has now presented with generalized edema and kidney failure. He has 4+ proteinuria with estimated Glomerular filtration rate of 35 mL/min/1.73 . What is the most likely kidney biopsy finding in this syndromic association ?
Answer
B. Focal segmental glomerulosclerosis
53
5y/M presents with recurrent hematuria, progressive nephropathy and sensorineural deafness. Hemogram shows thrombocytopenia and giant platelets. On testing you find normal collagen 3, 4 and 5. What is your most likely diagnosis ?
Answer
Question Cancelled
54
All the following are components of Renal angina Index (RAI) except
Answer
D. Urine output
55
Kocher-Debre-Semelaigne syndrome is characterised with hypothyroidism along with which of the following ?
Answer
A. Pseudohypertrophy
56
All the following are recently approved monoclonal antibodies for Asthma except
Answer
B. Obinutuzumab
57
4-year-old girl brought with poor growth, increased thirst and urination for the past 2-3 years; she drinks ~3 L of water and urinates 10 times a day. Physical exam was unremarkable except chronic malnutrition Labs: Na 154 mEq/L, K 4.2 mEq/L, Ca 9.3 mg/dL, HCO3 23.2 mEq/L, glucose 89 mg/dL, TSH 1.35 mU/mL. Urinalysis: no proteinuria/glycosuria, specific gravity 1.002. USG revealed B/L hydroureteronephrosis. Which further test would you perform to confirm the diagnosis ?
Answer
A. Water deprivation test
58
Wolfram syndrome is characterised by all of the following except
Answer
D. Thymus abnormalities
59
What is the most common cause of acquired hypothyroidism ?
Answer
C. Hashimoto thyroiditis
60
15-year-old girl presented with primary amenorrhea. Breast development and pubic hair started developing 2.5 years back. No acne/hirsutism/chronic drug intake/surgery in the past. O/E - SMR stage 2, Genitalia-grossly normal female Labs: TSH-3.7, FSH , LH , Estradiol , AMH , inhibin A USG: Small uterus and streak ovaries, Karyotype-46 XY
Answer
A. Swyer syndrome
61
Cerebral gigantism (Soto's syndrome) is characterised by following clinical features except
Answer
A. Rapid growth due to endocrine dysfunction
62
The following investigations aid in the diagnosis of Central precocious puberty except
Answer
Question Cancelled
63
Hypoparathyroidism, sensorineural hearing loss and renal anomaly syndrome occurs due to the following gene pathogenic variants
Answer
A. GATA3
64
Cushing syndrome is characterized by all the following except
Answer
A. Midnight cortisol levels < 4.4 μg/dL
65
What is the diagnostic yield of Exome Sequencing in Cerebral Palsy as per the recently published meta-analysis ?
Answer
C. 31-34%
66
A 8-month-old girl presents with extreme irritability and developmental regression. On examination, there is diffusely increased tone. CSF evaluation reveals increased protein. MRI shows Tigroid appearance. Which of the following tests would you perform for confirmation of the diagnosis ?
Answer
B. Galactocerebrosidase
67
Most likely cause of Multiphasic Acute disseminated encephalomyelitis (ADEM) is
Answer
D. Myelin oligodendrocyte glycoprotein antibody
68
All the following epilepsy syndromes are most likely to begin in Infancy except
Answer
C. Progressive myoclonic epilepsy
69
All the following features are associated with Lafora body disease except
Answer
D. ARX mutations
70
Which of the following is a FDA approved, level A evidence supported antiepileptic for the treatment of childhood absence epilepsy ?
Answer
D. Both 2 and 3
71
Childhood and Adolescent Migraine Prevention (CHAMP) study compared the efficacy of which of the following treatments for Migraine ?
Answer
A. Topiramate and Amitriptyline
72
A 5-year old boy presented with complains of progressive motor difficulties, personality changes, cognitive decline, dysarthria, spasticity and late onset dystonia; with "eye of the tiger" sign on MRI of brain. Which of the following is the most likely genetic mutation involved ?
Answer
B. PANK2
73
White cerebellar sign is a radiological sign seen in all of the following except
Answer
B. Posterior circulation stroke
74
5-year-old girl with progressive difficulty in walking, which worsens during the day and is better after night's sleep. The girl also has rigidity in the leg muscles and dystonic twisting of legs. Which of the following is the most likely drug of choice ?
Answer
A. Levodopa
75
All of the following are characteristic early manifestations of congenital syphilis except
Answer
D. Interstitial keratitis and nerve deafness
76
Risk factors indicating increased probability of occult bacteremia include all of the following except
Answer
B. WBC Count ≥ 10,000/μl
77
Regarding the laboratory diagnosis of bacterial pathogen, which of the following statement is not true ?
Answer
C. Trichrome stain is used for identifying the bacteria
78
A 6 month old child presented with recurrent infection in the skin, leading to a non-healing ulcer in the perianal area. He also gives a history of delayed cord separation. The complete blood count done in the local hospital showing a total WBC count of 90,000/μl. Functional absence of which CD marker is diagnostic ?
Answer
A. CD18
79
I am an antibiotic with the following characteristics 1. I will act by disrupts bacterial cell membrane function causing depolarization leading to inhibition of protein, DNA and RNA synthesis, which results in bacterial cell death. 2. Active against enterococci, staphylococci, streptococci and corynbacteria. 3. Should not be used for pneumonia as drug inactivated by surfactant. Identify the antibiotic :
Answer
C. DAPTOMYCIN
80
As per the 2021 AWaRE classification under antibiotic stewardship programme, which of the antibiotic is not in the Access Category ?
Answer
B. Azithromycin
81
Which of the following statements regarding Latent mycobacterial tuberculosis infection (LTBI) is correct ?
Answer
Question Cancelled
82
The commonest organism in any type of osteomyelitis
Answer
C. Staphylococcus aureus
83
Which of the following statements about antinuclear antibody is correct ? i. ANA as a screening test is not recommended for rheumatic disease since it is having low specificity. ii. Up to 50% of children testing positive for ANAs have no underlying rheumatological conditions. iii. A positive ANA test can be due to infection by parvovirus B19 infection.
Answer
B. Only i and iii
84
Which is the IL-1 receptor antagonist (biological therapy) studied in patients with juvenile idiopathic arthritis (JRA) ?
Answer
C. Anakinra
85
Which of the following statement is/are correct about haemoglobin ? i. Large amount of Hb F is found in β thalassemia major. ii. Levels of Hb > 3.0% are found in persons with β thalassemia trait. iii. Decreased Hb levels are found in patients with iron deficiency anemia and α-thalassemia syndromes.
Answer
D. All of the above i, ii and iii
86
The causes of Microcytic anemia with low reticulocte count include all of the following except
Answer
D. Haemoglobin C and E disorders
87
Which of the following statement is true regarding Iron ?
Answer
D. Cow's milk protein can cause chronic intestinal blood loss in infants
88
Which of the following is the predominant site of hematopoesis in a 20 week old fetus ?
Answer
B. Liver
89
You are performing the tuning fork test on a patient who presented to the OPD with the complaints of decreased hearing in the left ear. Which of the following tuning forks is most commonly used for the clinical assessment of that patient ?
Answer
C. 512
90
Which of the following satement is not a characteristic feature of shawachman Diamond Syndrome ?
Answer
A. Most patients have symptoms of protein malabsorption
91
Which of the following statement regarding Von Williebrands disease (vWD) is correct ? i. Platelet count is low in vWD Type 2B. ii. Desmopressin is used in all types of vWD. iii. Circulating factor VIII activity is low in vWD Type 2N.
Answer
B. Only i and iii
92
Hereditary deficiency of platelet storage granules occurs in
Answer
D. Gray platelet syndrome
93
All of the following are diagnostic tests for the establishing splenic dysfunction except
Answer
C. Flow cytometric EMA (eosin 5 maleimide) binding test
94
Which of the following feature is incorrectly matched in a otoscope finding of acute otitis media without perforation ?
Answer
D. Mobility - None
95
Syndromic causes of autosomal dominant Sensorineural hearing loss (SNHL) causes include all of the following except
Answer
A. Usher Syndrome
96
Which of the following statements regarding Refractive error in children are correct ? i. Myopia is infrequent in infants whereas incidence increases during the school years. ii. Myopia is more common in infants with a history of retinopathy of prematurity. iii. Convcave lens of appropriate strength to provide clear vision is used as the treatment of choice of Myopia.
Answer
D. i, ii and iii
97
Amaurotic cat's eye reflex is seen in all of the following conditions except
Answer
A. Peters anomaly
98
Identify the wrong match in related to drug eruptions in Pediatric patients
Answer
Question Cancelled
99
Which of the following statements regarding scabies is correct ? i. Even though burrows are characteristic lesions of scabies, in infants and children bullae and pustules are relatively common. ii. The treatment of choice of scabies is permethrin cream 10% for local application. iii. In immunocompromised children Ivermectin can be given at a dose of 200 μg/kg per dose orally for 2 doses.
Answer
B. i and iii
100
A "reverse" Ponsetti method of serial casting is recommended in the management of which condition ?
Answer
C. Congenital vertical talus
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