| Post Name | ASSISTANT PROFESSOR IN PATHOLOGY |
|---|---|
| Department | MEDICAL EDUCATION |
| Question Paper Code | 041/2018/OL |
| Category Code | 331/2016 |
| Date of Test | 9 August 2018 |
| Medium of Question | ENGLISH |
| Exam Type | Online Examination |
| Total Questions | 100 |
1
Garo Hills is located in
Answer
C. Meghalaya
2
The Gandhi Sagar Dam is constructed over which of the following river?
Answer
B. Chambal
3
In India Jowar and Ragi are largely grown in which of the following types of soil?
Answer
Question Cancelled
4
Name the Indian state with the longest coastal line
Answer
D. Gujarat
5
Choose the scheme started by the Government of India for providing food to senior citizens who cannot live on their own
Answer
B. Annapurna
6
Who was the leader of the Chittagong Armoury Raid?
Answer
A. Surya Sen
7
Which session of Indian National Congress was presided by Gandhiji?
Answer
C. Belgaum
8
Select the organization that secured the Nobel Peace Prize in 2017
Answer
B. International Campaign to Abolish Nuclear Weapons
9
Which of the following film was selected as the 'Best Feature Film' for the 65th Indian National Film Awards?
Answer
D. Village Rockstars
10
Who won the Nobel Peace Prize in Literature in the year 2016?
Answer
Question Cancelled
11
Who was the Guru of Thyccaud Ayyavu?
Answer
B. Vaikunda Swamikkal
12
How many gold medals were secured by India in the Gold Coast Commonwealth Games 2018?
Answer
A. 26
13
Who was the leader of Nair Service Society?
Answer
C. Mannathu Padmanabhan
14
Which district is known as the 'Gateway of Kerala'?
Answer
A. Palakkad
15
Who was the author of the book, 'Kanneerum Kinnavum'?
Answer
D. V.T. Bhattathiripad
16
Which district of Kerala has the highest percentage of literacy?
Answer
C. Kottayam
17
Which colonial power constructed the Thangasseri Fort?
Answer
B. Portuguese
18
Who was the first Chief Justice of Kerala?
Answer
D. K.T. Koshi
19
Who was the Governor General of India when the Vernacular Press Act was passed?
Answer
A. Lord Lytton
20
In the revolt of 1857, Rani Lakshmi Bai of Jhansi was defeated by the English General
Answer
C. Hugh Rose
21
Which of the following changes best describe the pathophysiology involved in the production of pulmonary edema in patients with congestive heart failure?
Answer
C. increased hydrostatic pressure
22
Factor V Leiden mutation
Answer
A. Predispose to thrombosis
23
Leukotrienes are derived from arachidonic acid through action of this enzyme
Answer
C. 5-Lipooxygenase
24
Which is characteristic of irreversible injury?
Answer
D. Cell membrane defects
25
Which of the following is known as the membrane attack complex
Answer
C. C 5b-C9
26
An arterial thromboembolic is most likely to produce a hemorrhagic infarct in which organ?
Answer
C. lungs
27
The antibody that mediates hypersensitivity reactions and is most commonly found on surface of mast cells
Answer
D. IgE
28
These cells can lyse tumor cells or virus infected cells without prior sensitization
Answer
C. NK cells
29
Deficiency in homogentisic oxidase results in this condition
Answer
B. Alkaptonuria
30
Which of the following finding is most valuable in confirming Goodpasture's syndrome?
Answer
A. diffuse linear staining of GBM with IgG
31
Which of the following disease of the heart presents as early cyanosis?
Answer
C. Truncus arteriosus
32
Which of the following diseases result from a familial absence of high density lipoprotein?
Answer
C. Tangier
33
The medical disorder of "Minamata disease" is due to exposure to high levels of
Answer
B. Mercury
34
Hemoglobin Bart's is composed of
Answer
B. Four gamma chains
35
The substitution of a single nucleotide base with a different base result in
Answer
D. Point mutation
36
A 17-year-old receives whole body radiation as part of a preparatory regimen for bone marrow transplantation. Which of the following cells and tissues in the body is most likely to remain unaltered by the effects of this therapeutic radiation?
Answer
A. Neurons of cerebral cortex
37
The role of p53 in maintaining the integrity of genome is by activating
Answer
B. BAX
38
Bernad-Soulier syndrome is a defect in platelet
Answer
B. Adhesion
39
Councilman bodies are seen in
Answer
B. Acute viral hepatitis
40
Mutation in BRCA-2 is located in
Answer
C. 13q 12-13
41
Most common paraneoplastic syndrome associated with squamous cell carcinoma of the lung.
Answer
A. Hypercalcemia
42
Which is NOT TRUE in Neuroblastoma
Answer
D. Nmyc amplification have a better prognosis
43
Which is NOT TRUE about TRALI
Answer
A. is commonly associated with transfusion of packed erythrocytes
44
Which of the following statements in NOT true of red infarcts?
Answer
B. Commonly found in the heart and kidneys
45
Disaccharidase deficiency is classified under which of the following major causes of malabsorption syndrome
Answer
C. Primary mucosal cell abnormalities
46
Which of the following is Oncogenic RNA virus
Answer
A. HTLV-1
47
Function of thiamine
Answer
B. coenzyme in oxidative decarboxylation of alpha ketoacids
48
Mutation in Bruton tyrosine kinase result in
Answer
B. X linked Agammaglobulinemia
49
The receptors on T cells used by the HIV strain that is effective in transmitting the infection is
Answer
D. CXCR4
50
Class I MHC molecules are encoded by gene loci EXCEPT
Answer
A. HLA-D
51
Where in the brain is Negri body located in rabies?
Answer
D. Neuron
52
Ritter disease is also known as
Answer
C. Staphylococcal scalded skin syndrome
53
Fungi within small cysts in the Virchow Robin perivascular space is characteristic of
Answer
D. Cryptococcus neoformans
54
Which of the following is NOT related to Alzheimer disease
Answer
C. Lafora bodies
55
The associated molecular change in the evolution of colorectal tumor from late adenoma to carcinoma is
Answer
B. inactivation of p53 chromosome 17p13
56
Which is NOT true of isochromosome
Answer
D. Isochromosome accounts for upto 15% of all cases of Klinefelter Syndrome
57
All are vitamin K dependent factors EXCEPT
Answer
B. Factor 6
58
Osteogenesis imperfecta is caused by deficiency in the synthesis of
Answer
A. Type I collagen
59
All are premalignant lesions of skin EXCEPT
Answer
B. Seborrheic keratosis
60
Which of the following components of blood is mainly responsible for transporting exogenous (dietary) triglyceride from the intestine following a meal?
Answer
B. Chylomicron
61
A liver biopsy of 45 year old man with a history of alcohol abuse shows cirrhosis, and individual hepatocytes contain red, globular inclusions positive for cytokeratin with immunohistochemical staining. Which of the following structural elements are these intracellular globules most likely to contain?
Answer
C. Intermediate filaments
62
Which is NOT True of Bombay blood group?
Answer
D. Express H antigen on erythrocyte
63
Embryonic hemoglobin is composed of
Answer
D. Zeta and epsilon
64
45-year old man has hepatosplenomegaly with pancytopenia. On biopsy of liver large cells are seen with a crumpled tissue paper appearance of cytoplasm. Which of the following may be deficient in this patinet?
Answer
A. Glucocerebrosidase
65
Which of the tumor marker is associated Breast cancer?
Answer
B. CA-15-3
66
Genomic Imprinting with Deletion in maternal chromosome is seen in
Answer
D. Angelmans syndrome
67
Which is true about Dilated cardiomyopathy?
Answer
A. results in systolic (contractile) dysfunction
68
Which is NOT TRUE of MPO-ANCAs?
Answer
D. Associated with polyarteritis nodosa
69
Vegetations Libman-Sacks endocarditis (LSE) are
Answer
A. small vegetations on either or both sides of the valve leaflets
70
Which of the following is NOT TRUE about hepcidin?
Answer
D. Hepcidin increases erythropoietin production
71
Which of the following is NOT true about PNH?
Answer
D. Increased NAP score
72
Hb A2 is increased in
Answer
B. Thalassemia minor
73
Hb H inclusions are seen in
Answer
D. Alpha thalassemia
74
Which is associated with better prognosis in CLL/SLL?
Answer
B. deletion of 13q14
75
Which of the following is NOT true about Anaplastic Large-Cell Lymphoma
Answer
A. t (2, 5)/p80 or ALK-1 is positive in all cases
76
Döhle bodies are
Answer
A. patches of dilated endoplasmic reticulum that appear as sky-blue cytoplasmic "puddles"
77
Collapse of lung secondary to air in the pleural cavity is an example of
Answer
C. Compression atelectasis
78
Which is NOT TRUE about Asbestos exposure
Answer
C. asbestosis is the most common pneumoconiosis in the world
79
Pulmonary hemorrhage syndromes are all EXCEPT
Answer
D. Pulmonary embolism
80
Which is NOT TRUE about Minimal Change disease
Answer
B. is the most frequent cause of nephritic syndrome in children
81
Renal osteodystrophy differs from nutritional and metabolic rickets due to the presence of
Answer
A. Hyperphosphatemia
82
The first event in the Pathogenesis of Cholesterol Stones is
Answer
B. Supersaturation of bile with cholesterol
83
Which of the following is NOT associated with familial primary hyperparathyroidism
Answer
C. MEN 2B
84
Which of the following is NOT associated with celiac disease
Answer
C. Tropheryma whippelii
85
All the following are associated with Tuberous sclerosis EXCEPT
Answer
D. Adenomatous polyps of GIT
86
Features of Autoimmune Hepatitis include all EXCEPT
Answer
D. Granulomatous destruction of small to medium sized intrahepatic bile ducts
87
Which of the following testicular tumor is most radiosensitive?
Answer
B. Seminoma
88
Which type of breast cancer has the highest incidence of bilaterality
Answer
D. Lobular carcinoma
89
All the following in cervical cancer prevention are recommendations by FDA (USA), EXCEPT
Answer
D. Cervical cancer screening by PAP smear to be discontinued
90
Endometrial hyperplasia is associated with all EXCEPT
Answer
A. Excess progesterone
91
Which of the thyroid cancer has the best prognosis
Answer
B. Papillary carcinoma
92
Following are common complications of pyogenic osteomyelitis EXCEPT
Answer
A. Spread to the adjacent joint
93
HLA B27 is associated with
Answer
C. Ankylosing Spondylitis
94
The enzyme used as a marker for alcohol abuse is
Answer
A. Gamma glutamyl transferase
95
The inflammatory lesion seen in acute appendicitis is initiated by
Answer
B. Luminal obstruction
96
The principal defect in chronic granulomatous disease is in
Answer
C. Oxidative burst
97
Serum Alpha feto protein level is elevated in
Answer
A. Hepatocellular carcinoma
98
Pneumocystis pneumonia typically in the lungs demonstrates a
Answer
B. intra alveolar cotton candy exudates` `
99
Severe deficiency of coagulation factor IX produces a disorder
Answer
B. Hemophilia B
100
The most common cause of acute bacterial meningitis in neonates is
Answer
C. E. Coli
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