| Post Name | Assistant Professor in Pharmacy - Medical Education |
|---|---|
| Question Paper Code | 034/2023/OL |
| Category Code | 561/2017 |
| Date of Test | 22 May 2023 |
| Medium of Question | KANNADA |
| Exam Type | Online Examination |
| Total Questions | 100 |
1
Modiļ¬ed Brontrager's test in Aloe is performed due to the presence of
Answer
B. C-glycoside
2
The crude drug used as an anti hypertensive
Answer
D. Catechu
3
The parameter of growth for assessing the relative contribution of cell aggregates and free cells to growth in culture medium is
Answer
C. Mitotic index
4
Indian liquorice is the other name of
Answer
B. Abrus precatorius
5
The gene transfer method which is not suitable for protoplasts
Answer
A. Biolistic method
6
Cycloeudesmol an antibiotic substance is isolated from
Answer
D. Red algae
7
Ash value is used to detect the following except
Answer
C. Decomposed products
8
Forskolin, used in treatment of cardiomyopathy is a
Answer
A. Diterpene
9
Formation of lignin compounds is by
Answer
C. Shikimic acid pathway
10
The plant growth regulator which act as selective weedicide or herbicide in high concentrations
Answer
B. Auxins
11
Who is proved existence of receptors ?
Answer
Question Cancelled
12
Lysosomes are unit membrane bound organelles that contain
Answer
C. Acid hydrolase
13
The most primitive cell in erythropoiesis
Answer
A. Pluripotent stem cell
14
Which vitamin is needed for synthesis of collagen, the main bone protein ?
Answer
A. Vitamin C
15
Which of the following is inhibitory neuro transmitter ?
Answer
Question Cancelled
16
At the point where the trachea divides in to right and left primary bronchi, an internal ridge called
Answer
B. Carina
17
Oestrogen act on
Answer
C. Nuclear receptor
18
Type I anaphylactic reactions, anaphylaxis is mediated by
Answer
C. IgE antibodies
19
The position of Dose response curve, on the dose axis is the index of
Answer
D. Drug potency
20
Drug which undergoes enterohepatic cycling
Answer
Question Cancelled
21
Name the partial agonist eļ¬ective for smoking cessation.
Answer
C. Verenicline
22
Benzodiazepine antagonist
Answer
D. Flumazenil
23
Teicoplanin belongs to
Answer
D. Glycopeptides
24
Name one luminal amoebicide
Answer
A. Diloxanide furoate
25
Azole antifungal agent active against Mucor mycosis
Answer
B. Posaconazole
26
Selective adrenoceptor antagonists
Answer
D. Tamsulosin
27
A macrolide antibiotic with signiļ¬cant activity against Mycobacterium leprae
Answer
C. Clarithromycin
28
Purine antimetabolite with cytotoxic and immunosuppressant action
Answer
A. Azathioprine
29
Aminoglycoside antibiotic having resistance to bacterial aminoglycoside modifying enzyme
Answer
D. Amikacin
30
Raltegravir is
Answer
B. Integrase inhibitor
31
In XYZ classiļ¬cation for inventory control the drugs are categorized on their
Answer
Question Cancelled
32
Which method is a useful tool in overall analysis of cost volume relationship in charging policy ?
Answer
C. Break-even point pricing
33
LDH3 the enzyme mainly concentrated in which tissue ?
Answer
B. Lungs
34
Pramlintide belongs to which class of drug ?
Answer
A. Amylin analogue
35
Trachoma is caused by which organism ?
Answer
D. Chlamydia trachomatis
36
One step dry chemistry method can be used to measure
Answer
A. Concentration of drugs in the body
37
Name the place where the ļ¬rst drug information centre is established.
Answer
B. University of Kentucky
38
What does Urea breath test for ?
Answer
D. To examine the presence of H. Pylori
39
Anti-CCP is the biological Marker for which disease ?
Answer
D. Rheumatoid Arthritis
40
Which is the method used for sterilization of thermo labile powders ?
Answer
A. Gaseous sterilization
41
In gradient elution technique
Answer
B. Two solvents that are completely miscible in each other and with diļ¬erent dielectric constant is used
42
The absorption maxima of 1, 4-dimethylcyohex-1, 3-diene using Woodward-Fieser rule is
Answer
A. 273 nm
43
Ferroin indicator is
Answer
B. Orthophenanthroline-ferrous complex
44
In infrared spectroscopy, for preparing solid samples, the solid sample is mixed with Nujol to a thick paste in
Answer
B. Mull technique
45
Which of the following statement is false about Mohr's method of titration ?
Answer
B. The solution to be titrated should be acidic
46
Ilkovic equation gives the relationship between
Answer
B. Diļ¬usion current vs concentration
47
Give the relative areas of multiplets of methylene protons in the proton NMR spectra of
Answer
B. 1 : 3 : 3 : 1
48
The molecular ion peak of methylene chloride in the mass spectrum will be at the m/z value
Answer
A. 84
49
Fourier transform NMR instruments records
Answer
B. Free induction decay signal
50
If the organic samples are contaminated with water and oxides of nitrogen and sulphur, the detector of choice in gas chromatography is
Answer
A. Flame ionization detector
51
Which of the following is equal to 5Ā¹ā°ā°?
Answer
D. 5Ā²ā° Ć 5āµ
52
Recombinant enzyme used for the treatment of Pompe disease is
Answer
A. -glucosidase
53
Example of Amino acid containing thioether group
Answer
B. Methionine
54
Isomerism exhibited by unsaturated fatty acids
Answer
C. Both 1 and 2
55
As per induced ļ¬t theory for enzyme substrate complex formation
Answer
A. The active site is not rigid and pre-shaped
56
Measurement of lowering of vapour pressure can be done by
Answer
D. All the above
57
Pick out the correct order of stability of carbocation relative to the substrate from which it is formed.
Answer
B. 3Ā° > 2Ā° > 1Ā° > CHāāŗ
58
Cobalt labelled cyanocobalamin is used in the
Answer
C. Both 1 and 2
59
Which of the following statement is true about amines ?
Answer
A. Primary amines undergo carbylamine reaction
60
Pyridine is less basic than aliphatic amines because the lone pair of electrons on N-atom in pyridine is in
Answer
B. hybrid orbital
61
Colterol is a
Answer
A. Selective -agonist
62
What happens when the substitution on the amino nitrogen in adrenergic agonists increase in size from hydrogen to methyl to isopropyl ?
Answer
B. receptor agonist activity decreases and -receptor agonist activity increases
63
Give an example of imidazopyridine derivative used as a hypnotic.
Answer
C. Zolpidem
64
The drug Meperidine should not be administered to patients receiving
Answer
A. Monoamine oxidase (MAO) inhibitor
65
Which of the following is an -Glucosidase inhibitor used as hypoglycemic agent ?
Answer
C. Both 1 and 2
66
Hammett substituent constant
Answer
D. All the above
67
Which of the following is the pro-drug of pralidoxime ?
Answer
A. Pro-2-PAM
68
IUPAC name of Ketamine is
Answer
A. 2-(2-Chlorophenyl)-2-(methylamino) cyclohexanone
69
Synthesis of Phenytoin from benzil takes place via
Answer
B. Benzilic acid rearrangement
70
Example of an iminostilbene derivative used as anticovulsant
Answer
A. Carbamazepine
71
For a new drug substance intended for storage in a refrigerator, the long term stability studies as per ICH guidelines are to be conducted at a storage temperature of
Answer
A. 5Ā°C Ā± 3Ā°C
72
Pick out the wrong statement.
Answer
D. Diļ¬erent areas within a manufacturing plant requires the same SOP (Standard Operating Procedure) for cleaning
73
With an increase in temperature, surface tension of water
Answer
B. Decreases
74
Pick out the correct statement
Answer
B. Colloidal particles can pass through a ļ¬lter paper
75
Which among the following has the highest HLB value ?
Answer
C. Sodium lauryl sulphate
76
Which among the following can be used for the determination of viscosity of a Newtonian liquid ?
Answer
D. All the above
77
The shelf life of a drug (assuming duration of retaining at least 90% of initial strength as shelf life) undergoing ļ¬rst order decomposition can be calculated using the formula
Answer
B. 0.104 divided by rate constant for decomposition
78
In a Fisher sub sieve sizer,
Answer
C. Surface area of a powder is determined by air permeability method
79
Who among the following is not an ex oļ¬cio member of the Drugs Technical Advisory Board ?
Answer
D. Minister of Chemicals and Fertilizers, Govt. of India
80
The chairman of Drug Enquiry Committee constituted in 1930
Answer
A. Col. R.N. Chopra
81
The Bacterial strain used for manufacture of BCG vaccine
Answer
B. Attenuated live strain of Mycobacterium Bovis
82
The active ingredient present in Dettol solution
Answer
A. Chloroxylenol
83
The pore size of millipore ļ¬lter GS grade used for aseptic processing
Answer
A. 0.22 0.02 m
84
During sterility testing, the inactivating agent used for inhibiting agents like phenol and alcohol is
Answer
B. Dilution
85
The solvent used inside the boilable catgat tube is
Answer
C. Toluene
86
The ļ¬rst FDA approved monoclonal antibody used to treat organ transplant rejection
Answer
C. Muromonab-CD3
87
Which of the following route of drug administration cannot be considered as extravascular ?
Answer
C. Intraarterial
88
Which among the following class of drugs is having the highest apparent volume of distribution ?
Answer
D. Amphetamines
89
Which of the following options is showing the rate of metabolism as deļ¬ned by Michaelis-Menten equation ?
Answer
B. (Vmax Cp)/(Km + Cp)
90
For drugs that are not systematically absorbed like antacids, bioequilivalence studies is carried out by
Answer
A. A surrogate marker with pharmacodynamic eļ¬ect
91
Which one of the following dryer is known as lyophilizer ?
Answer
B. Freeze dryer
92
What are the modes observed in a ball mill for size reduction ?
Answer
A. Impact and attrition
93
Which one of the distillation method is used to get sharp separation between component of the mixtures containing miscible volatile liquid having diļ¬erent but close boiling point ?
Answer
A. Rectiļ¬cation
94
Which one of the mixing equipment used for two immiscible liquids ?
Answer
C. Silverson mixer emulsiļ¬er
95
During compression, air entrapment may lead to
Answer
B. Capping and laminating
96
Pyrogens are
Answer
B. Bacterial Endotoxins
97
What are the characteristics of the mixed monolithic reservoir devices ?
Answer
C. Drug polymer matrix is layered by rate controlling membrane
98
The 00 size capsules can ļ¬ll the volume of
Answer
D. 0.95 ml
99
Hepta ļ¬uoro propane is
Answer
D. Propellent 227
100
Treated soda lime glass is called as
Answer
C. Type II
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