| Post Name | Assistant Professor in Pharmacy |
|---|---|
| Department | Medical Education |
| Question Paper Code | 088/2026/OL |
| Category Code | 691/2025 |
| Date of Test | 9 May 2026 |
| Exam Type | Online Examination |
| Total Questions | 100 |
1
The principal cinchona alkaloid used therapeutically as an antiprotozoal drug ______________.
Answer
C. Quinine
2
Which among the following opium compounds lacks narcotic properties?
Answer
D. Narcotine
3
Which among the following is an example of a colorful tetraterpene compound?
Answer
B. Beta-carotene
4
The reagent used to liberate alkaloids as salts from plant components is _______________.
Answer
D. Sodium carbonate
5
Raymond's test is a chemical test for:
Answer
A. Cardiac glycosides
6
The plant growth regulator used in the brewing industry to speed up the malting process is ______________.
Answer
C. Gibberellic acid
7
Which among the following contains both alkaloid and glycoside as its constituents?
Answer
C. Nuxvomica
8
The marine derived compound which has anti parasitic action and also used in epilepsy modelling is _______________.
Answer
C. Kainic acid
9
The colour of fluorescence observed during Schoenteten's test is ______________.
Answer
A. Green
10
When a transverse section of Clove is treated with a strong solution of potassium hydroxide ____________ shaped crystals are formed.
Answer
B. Acicular
11
Some drugs are placed under orphan drugs due to the following factors except
Answer
D. Poor Quality
12
T1/2 of Paracetamol is
Answer
Question Cancelled
13
Tachyphylaxis is
Answer
A. Acute tolerance to drugs
14
Cytokinesis begins in
Answer
B. Late anaphase
15
Simple Cuboidal epithelium is found in
Answer
B. Retina of eye
16
The drug which undergoes Hoffman elimination
Answer
C. Atracurium
17
During embryonic development, the percentage of cardiac muscle fibers that become autorhythmic fibers are:
Answer
A. About 1%
18
Inspiration follows
Answer
C. Boyle's law
19
Different stages of anaesthesia are except
Answer
D. Stage of Depression
20
Knee cap is otherwise termed as
Answer
A. Patella
21
An organism that cause haemolytic uraemic syndrome, leads to acute renal failure in children
Answer
A. Escherichia coli
22
Which food additive-containing preparation should be used with caution in children with Phenylketonuria?
Answer
B. Aspartame
23
Schwartz equation, used to calculate creatinine clearance
Answer
C. Creatinine clearance (mL/min/1.73 m²) = k × height (cm)/serum creatinine (mmol/L)
24
Recombinant portion of human parathyroid hormone used to reduce vertebral and non vertebral fractures in post menopausal woman
Answer
A. Teriparatide
25
A drug that induce idiosyncratic (Type B) hepatotoxicity
Answer
C. Isoniazid
26
Secretary of Pharmacy and Therapeutic committee
Answer
A. Pharmacist
27
Specific antibody test used to detect Rheumatoid Arthritis even before symptoms become severe
Answer
C. Anti cyclic citrullinated peptide antibody (Anti CCP antibody)
28
Kaposi's sarcoma in people with HIV infection may be triggered by infection with
Answer
A. Human herpes virus (8)
29
Left ventricular dysfunction can result from
Answer
D. All above
30
Only anti TB drug that is bactericidal against all three population (Extra cellular, intermittent and intracellular Mycobacterium tubercle bacilli (MTB)
Answer
B. Rifampicin
31
Which of the following are examples for reversible anticholinesterases?
Answer
B. Neostigmine and Donzepil
32
Cyproheptadine primarily blocks
Answer
A. 5-HT2A receptor
33
Clinical use of 1, 3, 7 Trimethylxanthine is
Answer
C. Apnoea in premature infants
34
Insulin aspart is an insulin analogue produced from human insulin by
Answer
B. replacing proline with aspartic acid at B28
35
Which of the following statement is incorrect
Answer
D. Stavudine is fluorinated cytidine analogue
36
Drug of choice for treatment of Clostridium difficile superinfection is
Answer
B. Metronidazole
37
Mechanism of action of dutasteride in treatment of male pattern baldness is
Answer
A. 5 -reductase inhibition
38
Which among the following drugs causes greater cochlear damage?
Answer
A. Amikacin and Kanamycin
39
Hypertrichosis occurs in patients receiving Minoxidil is probably a consequence of
Answer
B. Opening of K+ channel
40
Quinine used for treatment of malaria is
Answer
A. Levo rotatory
41
In Karl Fischer method, one mole of water reacts with how many moles of iodine?
Answer
C. 1
42
In reversed-phase chromatography,
Answer
B. The most polar component is eluted first
43
In Flame Ionisation Detectors, the sample is pyrolysed using:
Answer
B. Hydrogen and Air
44
Thermogravimetric analysis is a useful technique in detecting:
Answer
Question Cancelled
45
Horseradish peroxidase is a commonly used reagent in which of the following analytical techniques?
Answer
A. ELISA
46
Deviations in Beer-Lambert Law occur when:
Answer
A. Concentration changes cause refractive index variation
47
Tetramethylsilane is used as internal standard in NMR spectroscopy because:
Answer
C. It gives a single sharp peak
48
Which type of formulation interactions can be detected by X-ray Diffraction?
Answer
B. Solid-state interactions
49
Choose the correct logical sequence of instrument qualification in Quality Assurance:
Answer
A. DQ, IQ, OQ, PQ
50
Which among the following ICH Quality Guidelines relate to stability testing of pharmaceuticals?
Answer
A. ICH Q1
51
The number of peptide groups in oxytocin
Answer
B. 9
52
Which buffer maintains blood pH (~7.4)?
Answer
B. Bicarbonate buffer
53
Okazaki fragments are joined together by
Answer
A. DNA ligase
54
Which of the following compounds yields a yellow precipitate when warmed with a mixture of iodine in aqueous sodium hydroxide?
Answer
D. Acetophenone
55
Where is the transition state found in a free energy diagram?
Answer
C. At the highest energy point on the curve
56
Which statement is correct about Simmons smith reaction
Answer
B. Reaction is stereospecific
57
Which one of the following is a mono carboxylic acid?
Answer
C. Arachidic acid
58
What is the systematic name of isoprene?
Answer
A. 2 methyl 1, 3 - butadiene
59
The nitrogenous base that is never found in the genetic code
Answer
C. Thymine
60
Iron in the mucosal cells binds with the protein
Answer
B. Ferritin
61
A drug that increases insulin sensitivity via PPAR - activation is
Answer
C. Pioglitazone
62
The structural modification that improves selectivity of 2 agonists?
Answer
B. Bulky substituent on amino group
63
The unique Local Anaesthetic that does not contain a tertiary amine
Answer
D. Benzocaine
64
One of the primary precursors for the synthesis of Diazepam is
Answer
A. 2-amino-5-chloro benzophenone
65
The following is the chemical structure of
Answer
C. Trimethoprim
66
The anti-HIV drug that inhibits protease enzyme
Answer
B. Ritonavir
67
One of the primary antidotes for non-depolarizing neuromuscular blocking drugs
Answer
D. Neostigmine
68
The drug of choice to treat edema resulting from liver cirrhosis
Answer
C. Spironolactone
69
Substitution at position 2 of Phenothiazine nucleus with chlorine results in
Answer
A. Increased activity
70
Which standard parameter is crucial in evaluating docking accuracy?
Answer
B. Root Mean Square Deviation
71
A preparation containing Diamorphine will be classified as an opium derivative only if:
Answer
D. No minimum limit
72
Which among the following is a spurious drug?
Answer
B. Drugs labelled with the name of false manufacturer
73
Proof spirit contains
Answer
C. 57.1% v/v ethyl alcohol
74
Why is line clearance performed before starting a new batch?
Answer
A. To ensure no remains of the previous product or documentation are present
75
Non-obviousness is a concept specifically used to determine which of the following requirements for a patent grant?
Answer
B. Inventive step
76
According to the ICH Q1A (R2) guideline, a "significant change" for drug product is defined as meeting any of the following criteria EXCEPT:
Answer
C. Softening of a suppository or melting of a cream
77
Stokes' law applies to a suspension, only when the Reynolds number is
Answer
D. Below 0.2
78
Which among the following is a hydrophilic colloid?
Answer
A. Insulin
79
Reciprocal of mobility refers to
Answer
D. Plastic viscosity
80
Spreading coefficient is positive when :
Answer
A. Surface tension (S T) of sub layer liquid is greater than the sum of S T of spreading liquid and interfacial tension between spreading and sub layer liquid.
81
The immunoglobulin with a secretory component at the mucous membrane and prevents infection by inhibiting adherence of microorganisms to the host cells.
Answer
B. IgA
82
The cell which is made by fusing an antibody-producing B cell with a cancerous cell.
Answer
D. Hybridoma
83
In absorption kinetics, a plot of the amount of drug remaining to be absorbed against time yields a straight line, such kinetics is
Answer
A. Zero Order Kinetics
84
The test organism used for the microbiological assay of Gentamicin
Answer
C. Staphylococcus epidermis 12228
85
The fraction of drug removed from the plasma in a single passage through the organ is known as
Answer
B. Extraction ratio
86
Low molecular weight compounds from the environment, or a drug that act as immunogens by chemically complexing to a larger molecule or on the cell surface and stimulates the immune system of the host
Answer
C. Haptens
87
A clean room in which the particle count in the air is not more than 100 per cubic foot, of 0.5 micrometre
Answer
A. Class 100 clean room
88
The following method of sterilization is not used for catgut
Answer
D. Heat sterilization in the presence of moisture
89
Which among the following is not a characteristic feature of nonlinear pharmacokinetics?
Answer
B. Area under the curve is proportional to the dose
90
Insulin immobilized using degradable calcium phosphate nanocrystals on a self-assembling nanocrystalline ceramic core coated with a glassy pyridoxal 5 phosphate and the resulting product comes under the category of
Answer
A. Aquasome
91
The antimicrobial preservative used in ophthalmic preparation is all except:
Answer
Question Cancelled
92
Which excipient is commonly involved in Maillard reactions in pharmaceuticals?
Answer
B. Lactose
93
Which of the following statements about triethanolamine soap in incorrect?
Answer
D. It is stable in strongly acidic conditions
94
Which of the following materials is least suitable for fluidized bed drying?
Answer
B. Cohesive fine particles
95
What is the permissible limit of bacterial endotoxins in sterile water for injection?
Answer
A. Not more than 0.25 units per mL
96
What is the flow pattern produced in a paddle mixer during liquid mixing?
Answer
C. Radial and tangential
97
What is the approximate particle size obtained in microencapsulation by the air suspension method?
Answer
A. 35 to 5000 m
98
What is the chemical nature of pyrogens?
Answer
D. Lipopolysaccharides
99
Identify the propellant used in the preparation of topical pharmaceutical aerosols.
Answer
A. Propane
100
How does oleic acid act as a permeation enhancer in transdermal drug delivery system?
Answer
B. It forms microchannels in the stratum corneum
Discussion
Ask a doubt or share a tip.
No comments yet — start the discussion.