| Post Name | Assistant Professor in Physiology |
|---|---|
| Department | Medical Education Category No : 644/2021 |
| Question Paper Code | 095/2022/OL |
| Category Code | 644/2021 |
| Date of Test | 2 December 2022 |
| Exam Type | Online Examination |
| Total Questions | 100 |
1
Pulse rate in atrial ļ¬brillation is
Answer
A. 120-180/min
2
The percentage of blood that is present in capillaries is
Answer
A. 5%
3
Angiotensinogen is produced by
Answer
A. Liver
4
The most sensitive index of myocardial infarcition is a rise in the plasma level of this enzyme
Answer
C. Creatine kinase MB
5
y descend in JVP is due to
Answer
C. Opening of tricuspid valve
6
All of the following occur when the blood ļ¬ows through the capillaries except
Answer
B. š»šš2 dissociation curve shifts to the left
7
The vasodilation producdd by š¶š2 is maximum in
Answer
B. Brain
8
Compensatory cardiovascular adjustment during prolonged standing is due to
Answer
A. Operation of baroreceptor mechanism
9
Myocardial oxygen demand is
Answer
B. Directly proportional to heart rate
10
The reļ¬ex that helps in maintain celebral blood ļ¬ow constant despite the increase in ICP.
Answer
A. Cushings reļ¬ex
11
Serum diļ¬ers from plasma
Answer
B. in lacking ļ¬brinogen
12
The last and ļ¬nal stage of formation of erythrocytes
Answer
A. Reticulocyte
13
Philadelphia chromosome is seen in the following disease
Answer
C. Chronic myeloid leukemia
14
The type of antibodies formed ļ¬rst after exposure to antigen
Answer
B. IgM
15
Treatment of toxic levels of methemoglobin
Answer
A. methylene blue
16
The presence of antibodies already bound to red blood cells as in haemolytic disease of newborn or autoimmune acquired haemolytic anemia is detected by
Answer
A. Direct coombs test
17
The cause of increased aļ¬nity of HB for oxygen as preservation injury in blood collected in ACD or CPD is
Answer
A. Decrease in 2, 3 biphospho D-Glyceric acid
18
The plasma level of following substances falls more rapidly during storage
Answer
B. Fibrinogen
19
Exchange transfusion is useful in the treatment of
Answer
A. Hemolytic disease of Newborn
20
Which statement is true about von. Willbrand's disease?
Answer
Question Cancelled
21
All the heterotrimetric G protein-coupled receptors that have been characterized to date are proteins that span the cell membrane 7 times and are called
Answer
B. Serpentine receptors
22
Nernst potential of sodium is
Answer
C. +61 mv
23
Gap junctions are present in
Answer
D. Smooth muscle
24
Smallest ļ¬lamentous structure that form cytoskeleton of cell
Answer
C. Microļ¬laments
25
The mechanism of action of Colchicine is by
Answer
C. By destroying mitotic spindle and arresting mitosis
26
Accessory muscle of inspiration
Answer
B. Sternocleidomastoid
27
Functional residual capacity is the sum of
Answer
A. Residual volume and Expiratory reserve volume
28
Contraction of External intercostal muscles causes ribs to move
Answer
C. Forwards and upwards
29
Shift to right of š2 dissociation curve is caused by
Answer
C. Increase in šš¶š2
30
Which of the following statement is/are correct about Surfactant? I. Secreted by type 1 alveolar cells II. Maintains alveolar stability III. Deļ¬ciency in infants causes infant respiratory distress syndrome
Answer
B. Only II and III
31
Respiratory acidosis is compensated by the kidneys by
Answer
A. Increased š» +ion secretion
32
Anion gap refers to the diļ¬erence between
Answer
D. Cations other than šš +and anions other than š¶š and š»š¶š3ā
33
Which of the following statement is true about 'Histotoxic Hypoxia'?
Answer
C. A - V šš2 diļ¬erence is low
34
Inspiratory "Ramp" Signal is produced by
Answer
A. Dorsal respiratory group of neurons
35
Symptoms of Caisson Disease are due to
Answer
D. Blockage of blood vessels by š2
36
Oxyntic cells in the stomach secrete
Answer
D. Hydrochloric acid
37
Secretin acts on the pancreatic ducts to cause the secretion of pancreatic juice
Answer
A. Rich in š»š¶š3ā concentration ā
38
The two primary bile acids formed in the liver are
Answer
B. Cholic acid and chenodeoxycholic acid
39
š¶š enters enterocytes from the interstitial ļ¬uid via ā
Answer
A. šš + ā š¾ + ā 2š¶š cotransporters ā
40
All are actions of Cholecystokinin except
Answer
C. Relaxation of pyloric sphincter
41
Steatorrhea is caused by all except
Answer
D. Hyposecretion of gastric acid
42
All are true about short chain fatty acids except
Answer
C. They are formed by the action of colonic bacteria on lipids
43
All are true about migrating motor complex except
Answer
D. Gastric secretion, bile ļ¬ow, and pancreatic secretion decrease during MMC
44
Hartnup disease is caused due to congenital defect in the mechanism of transport of
Answer
A. Neutral amino acids in the intestine and renal tubules
45
All are true regarding iron absorption except 2
Answer
B. Absorption occurs in the jejunum
46
GFR is increased when
Answer
A. Hydrostatic pressure in the glomerular capillaries increases
47
Loss of function mutation of paracellin 1 gene leads to
Answer
D. šš + and š¶š + loss in the urine
48
šš + is reabsorbed in proximal tubule via
Answer
B. Na-H exchanger
49
Bartter's syndrome is characterized by
Answer
Question Cancelled
50
Which of the following statement(s) is/are correct about the operation of loop of Henle as a countercurrent multiplier? I. High permeability of the thin descending limb to solutes ā II. Active transport of šš + and š¶š out of the thick ascending limb III. Inļ¬ow of tubular ļ¬uid from the proximal tubule with outļ¬ow into the distal tubule
Answer
C. II and III
51
Which of the following statement(s) is/are correct about the factors aļ¬ecting šš + reabsorption? I. Circulating levels of aldosterone II. Circulating level of ADH III. Rate of tubular secretion of š» +and š¾ +
Answer
B. I and III
52
Diuretic Furosemide acts by
Answer
A. Inhibiting the Na-K-2Cl cotransporter in the thick ascending limb of the loop of Henle
53
Volume of urine in the bladder that normally initiates reļ¬ex contraction is
Answer
B. 100-200 ml
54
Main source of heat loss from the body is by
Answer
B. Radiation and conduction
55
Substance used to measure GFR should be
Answer
A. Easily ļ¬ltered by the tubules
56
Which of the following statement is/are correct regarding regenerative changes in an axon? (i) Schwann cell on either side of injured site multiply by mitosis to form a growth cone (ii) Neuroļ¬brils starts growing from tip of the proximal stem called sprouting (iii) Out of many Neuroļ¬brils only one will ļ¬nd the way through the regeneration tube and reaches the target structure.
Answer
C. Only (ii and iii)
57
Following are true about Gap Junctions except (i) Provide low resistant bridge for rapid spread of excitation (ii) Present in cardiac muscle (iii) Responsible for plasticity of smooth muscle (iv) They are electrical synapses
Answer
B. Only (iii)
58
A business man after a cocktail party falls into a deep sleep with his right arm under his head. Very next morning when he was awaken, he is unable to move his right arm. But it tingles and pain sensation is intact on the right arm. What is the reason for the loss of motor function of his right arm?
Answer
C. A-ļ¬bers are more sensitive to pressure than C-ļ¬bers
59
A statement which is false regarding action potential is (i) In mammalian heart depolarization last about 2ms (ii) The slow return of š¾ +channel to the closed state contribute to the after hyperpolarization (iii) Voltage gated š¾ + channels bring the action potential to an end cause closure of their gate through a positive feed back
Answer
A. Only (iii)
60
Which of the following statement is/are correct about Channel Myopathies? (i) Hyperkalemic periodic paralysis is associated with mutation in šš +channel (ii) Malignant hyperthermia can respond to general anaesthetic like Halothane (iii) Paramyotonia congenita is associated with mutation in šš +channel
Answer
D. All the above (i, ii and iii)
61
Decerebrate animal shows all the features except (i) Absence of Righting reļ¬ex (ii) Opisthotonus (iii) Increased muscle tone in Flexor group of muscle (iv) Can stand unsupported
Answer
D. Only (iii)
62
Which of the following is/are correct statement about Paciniam corpuscle? (i) Slowly adapting receptors (ii) Respond maximum to sustained touch (iii) Found in less number in Mesentery (iv) Found in large number in the Skin and Subcutaneous tissue
Answer
Question Cancelled
63
Lesions of Posteroventral nucleus of Thalamus result in (i) Thalamic phantom limb (ii) Intention tremor (iii) Choreoathetosis (iv) Thalamic hand
Answer
Question Cancelled
64
Statement which is/are true about EEG are (i) EEG of Grandmal epilepsy is a high frequency low voltage pattern (ii) Psychomotor epilepsy is characterized by lower than normal frequency waves (iii) Petitmal epilepsy is characterized by a spike and dome pattern (iv) Sleep spindle appear during stage III of NREM sleep
Answer
B. Only (ii and iii)
65
Following are seen in Huntington's disease except (i) Hypokinetic movements (ii) Slurred speech (iii) Dermentia (iv) Death usually within 10 to 15 yrs after the onset of symptom
Answer
A. Only (i)
66
Which of the following statement is/are true regarding Aphasias? (i) They are abnormalities of language functions that are not due to defects of vision or hearing or to motor paralysis (ii) They are caused by lesions in the Categorical hemisphere (iii) In nonļ¬uent aphasia, the lesion is in Wernicke's area
Answer
C. Only (i and ii)
67
Circumventricular organ include the following structures except
Answer
D. Pineal gland
68
Statement which is/are false regarding Neuropathic pain (i) Causalgia is an example for neuropathic pain (ii) Reļ¬ex sympathetic dystrophy is often present (iii) Often accompanied by hyperalgesia and allodynia (iv) Skin in the aļ¬ected area is thick and there is decreased hair growth
Answer
B. Only (iv)
69
Following statement is/are true about Demyelinating diseases (i) Multiple sclerosis is the most common demyelinating disease of the Central Nervous System (ii) The viral antigen theory regarding multiple sclerosis indicate that it's incidence is greater in tropical region than in temperature region (iii) In Landry-Guillian-Barre's syndrome complete recovery is possible in most of the cases
Answer
A. Only (i and iii)
70
Two of the most unusual nonclassic neurotransmitters in the Autonomic Nervous System are
Answer
D. ATP and Nitric Oxide
71
Which of the following statement is/are false about Purkinje cells of Cerebellum? (i) They are the principal cells of Cerebellum (ii) Each purkinje cell receives powerful synaptic contact from just a single climbing ļ¬ber, which comes from a cell in the Superior Olivary Nucleus (iii) Each purkinje cell receives a synapse from 150000 parallel ļ¬bers, which originate from the tiny granule cells of the Cerebellum
Answer
B. Only (ii)
72
Which of the following is not a risk factor of Alzheimer disease?
Answer
C. Loss of GABA ergic pathway to the Globus pallidus
73
Following statement is/are true about Horner syndrome (i) Bilateral Ptosis, mitosis and anhidrosis are the key features (ii) Cocaine treatment have less eļ¬ect (iii) Less norepinephrine in the synaptic cleft (iv) In case of post ganglionic Horner syndrome, solution containing hydroxyamphetamine can be given
Answer
B. Only (ii, iii and iv)
74
Which of the following statement is/are false about cerebellum? (i) The two main inputs to the cerebellar cortex are Climbing ļ¬bers and Mossy ļ¬bers (ii) Spinocerebellum is the phylogenetically the newest part of Cerebellum (iii) Cerebrocerbellum is the largest part of the human cerebellum (iv) Palaeocerebellum helps in the regulation of muscle tone
Answer
A. Only (ii)
75
Examples in which visaeceral aļ¬erents overwhelm corticol functions are (i) Nausea, hunger and Visceral pain (ii) Bladder and bowel distention (iii) Hyperthermia and hypothermia (iv) Dyspnea
Answer
Question Cancelled
76
Which of the following is/are not involved in color vision? (i) Activation of a pathway that signals the diļ¬erence between S cone responses and the sum of Land M cone responses (ii) Geniculate layers 3-6 (iii) P-Pathwah (iv) Area V3A of visula cortex
Answer
D. Only (iv)
77
Which of the following is/are correct statement about Olfactory receptors? (i) Human olfactory epthelium contains 1-2 million of bipolar olfactory sensory neurons (ii) Dendrites of each neuron terminates in a knob containing 10 to 20 cilia (iii) The cilia are unmyelinated process of about 20 šmin length (iv) The cilia contains speciļ¬c receptors for odorants
Answer
Question Cancelled
78
An 8 year old boy School met with at road traļ¬c accident and his MRI revealed damage to the brain including the periamygdaloid, piriform and entorhinal cortices. Which of the following sensory deļ¬cit is he most likely to experience?
Answer
D. Taste and odour abnormalities
79
Which of the following statement is/are wrong about Taste Sensation? (i) Many G-protein linked receptors in the human genome are taste receptors for bitter taste (ii) Sweet taste is triggered by š» + ions (iii) A 10Ā° degree change in concentration of the substance being tasted is necessary before an intensity diļ¬erence a be detected (iv) Substances that taste sweet are acting via G-protein gustducin
Answer
B. Only (ii and iii)
80
Which of the following condition result in sensoneuronal deafness?
Answer
C. Miniere's disease
81
Presence of non diļ¬usible ion on one side of membrane leads to the distribution of diļ¬usible ions in a predictable way. This is explained by
Answer
B. Gibbs Donnan equation
82
Which of the following is true about spliceosomes
Answer
B. Eliminates introns of some genes
83
Hormone sensitive lipase
Answer
A. Catalyses the breakdown of triglycerides in adipose tissue
84
Eļ¬ects of microgravity includes
Answer
D. None of the above
85
Translation is
Answer
A. Conversion of information encoded in mRNA to a protein
86
In true hermaphroditism
Answer
C. Individual have both ovaries and testes
87
Constitutional precocious puberty is due to
Answer
D. None of the above
88
Sprematids mature to spermatozoa in
Answer
Question Cancelled
89
Hormone responsible for the ļ¬nal progression to ovulation stage and follicular growth is
Answer
B. LH
90
Milk ejection is the function of
Answer
A. Oxytocin
91
All are examples of negative feed back control except
Answer
D. LH surge
92
Hypothalamo-hypophyseal tract connect hypothalamus with
Answer
B. Posterior lobe of pituitary
93
ANP causes 1. Aļ¬erent arteriolar constriction 2. Relaxation of mesangial cells 3. Increases capillary permeability 4. Inhibits renin secretion
Answer
B. 2, 3 and 4 are correct
94
False statement about GH is
Answer
A. Causes an increase in plasma cholesterol
95
Hyperthyroidism is characterised by all except
Answer
D. increased weight gain
96
Example for amino acid derived hormone is
Answer
A. Serotonin
97
Insulin stimulated glucose uptake in adipose tissue take place through
Answer
B. GLUT 4
98
The most common cause of adreno-genital syndrome is due to deļ¬ciency of
Answer
C. 21Ī² hydroxylase
99
Action of parathormone includes
Answer
C. Calcium reabsorption and phosphaturia
100
Regarding melatonin all are true except
Answer
A. It is synthesised from tyrosine
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