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Kerala PSC Laboratory Technician Gr II 152/2024,203/2024,426/2024,435/2024 Previous Question Paper – 069/2025

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Post NameLaboratory Technician Gr II 152/2024,203/2024,426/2024,435/2024
Question Paper Code069/2025
Category Code152/2024, 203/2024, 426/2024, 435/2024, 530/2024, 612/2024
Date of Test23 June 2025
Medium of QuestionENGLISH
Exam TypeOMR Examination
Total Questions100
1
Which of the following anticoagulants is used for coagulation studies?
Answer
A. Trisodium citrate
2
lron deficiency anemia is characterized by all, EXCEPT
Answer
D. RDW < 13%
3
Which cytochemical stain shows block positivity in lymphoblast?
Answer
B. PAS
4
Which of the following diluting fluids is used for absolute eosinophil count?
Answer
C. Dunger's
5
In peripheral smear staining by Leishman stain, undiluted stain is added first and then water is added only after 2 minutes. During this initial 2 minutes, there is
Answer
D. Fixation of smear 69/2025 3
6
lncreased number of eosinophils in sputum is seen in
Answer
A. Bronchial asthma
7
lf floccular precipitate is obtained in heat and acetic acid test of urine, then the amount of protein in urine is graded as
Answer
C. 3+
8
Semen diluting fluid contains
Answer
B. Sodium bicarbonate
9
Cobweb coagulum on standing is formed in CSF in which type of meningitis?
Answer
D. Tuberculous
10
What is the amount of reducing sugar present if Benedict's qualitative test in urine gives orange precipitate?
Answer
C. 1.5-2 g/dl
11
Read the following statements about "Determining the end point of decalcification" i)  Mechanical or physical method can be used for determining the end point of Decalcification. ii) E lectrophoresis method can be used for determining the end point of Decalcification. iii) C hemical method can be used for determining the end point of Decalcification. iv) R adiology or X-ray method can be used for determining the end point of Decalcification.
Answer
D. i, iii & iv are correct
12
Regarding clearance angle in a plane wedge knife used in a Rotary microtome, pick the correct response.
Answer
C. The clearance angle of a plane wedge knife is the angle between the block face and the knife's lower facet
13
Among the following statements, select the main advantage of using automated tissue processing machine.
Answer
A.  Automated tissue processors can process the tissue even when there is no technician around and even after working hours
14
Among the following statements, all are correct, Except
Answer
A. Periodic acid-Schiff (PAS) stain is used to identify elastic tissue in sections
15
All of the following statements about Frozen Sections are correct, Except
Answer
B. Frozen sections are very thin sections which can be studied very easily
16
Among the following fixatives, which one comes close to being an ideal fixative for "Fine Needle Aspiration Cytology (FNAC)"?
Answer
D. 95% Ethyl Alcohol
17
Among the following statements select the incorrect one.
Answer
D. Leishman's stain is the best stain for studying exfoliated cells in body fluids. 6 69/2025
18
Read the following statements about Barr Body and select the correct response: i) Barr bodies are the inactive X chromosome in females ii) Barr bodies are seen as well-defined body which stains intensely with nuclear dyes inside the nucleus at the edge. iii) Buccal smears are used for demonstration of Barr body iv) People with XXY chromosomal pattern may have two Barr bodies v) Crystal violet stain can be used to demonstrate Barr body vi) Barr bodies are seen inside the nucleus of all cells in females
Answer
A. i, ii & v are correct
19
Read the following statements about "Liquid-based cytology" and select the best response: i) Liquid-based cytology is a technique for collecting cytological samples which can be used to detect cervical cancer. ii) Liquid-based cytology involves suspending cells from a sample in a preservative, then spreading a thin layer of the cells onto a slide for examination. iii) Obtaining samples for liquid-based cytology is by taking cervical biopsy. iv) Liquid-based cytology improves fixation, reduces obscuring factors and allows for standardized cell transfer. It also allows for additional testing of the sample, such as for Human Papillomavirus (HPV).
Answer
B. i, ii & iv are correct
20
The cell block
Answer
D. The main disadvantage is that cell block slides cannot be stored for retrospective studies.
21
Which of the following statements is false?
Answer
B. The D negative phenotype is most common in people of African ethnicity
22
In extravascular hemolysis
Answer
C. Refers to the consumption of antibody and or c3b bound red cells by phagocytosis
23
In Direct Antiglobulin Test
Answer
A. The strength of the observed agglutination is indirectly proportional to the amount of bound protein
24
Cryoprecipitate is
Answer
D. It contains around 80-120 U of Factor VIII, about 150 mg of fibrinogen and also contains fibronectin and Factor XIII
25
Which group system is X linked dominant?
Answer
A. Xga blood group system
26
Name the term which defines the presence or absence of extra copies of a few chromosomes.
Answer
B. Aneuploidy
27
Which of the following chromosomal aberration shows pseudo dominance?
Answer
A. Deletion
28
The term chromosome was coined by
Answer
B. Waldeyer
29
Which of the following claims concerning chromosomal end is correct?
Answer
C. The end of chromosome are called telomere
30
Which among the following is also called high throughput sequencing?
Answer
B. Next generation sequencing
31
The term vaccine was coined by
Answer
C. Louis Pasteur
32
Temperature and time required for sterilization in hot air oven is
Answer
B. 160Β°C for 2 hrs
33
Which colour coded-bag is used for the disposal of expired medicines?
Answer
A. Yellow
34
Which of the following is used for the sterilization of disposable plastic items?
Answer
D. Ethylene oxide
35
Which is the commonly used method for the treatment of microbiological lab waste?
Answer
B. Autoclaving
36
The object appears bright against a dark background in
Answer
D. Dark ground microscope
37
India ink staining is used to demonstrate
Answer
C. Capsule
38
All of the following are the examples of enriched media, except
Answer
D. Deoxycholate citrate agar
39
Triple sugar iron agar medium contains all of the following carbohydrates, except
Answer
C. Mannitol
40
Which is the method used for determining minimum inhibitory concentration of an antibiotic?
Answer
A. Broth dilution method
41
Which is the recommended transport medium for stool specimens suspected to contain Vibrio cholerae?
Answer
A. Venkatraman-Ramakrishnan medium
42
The most common commensal in human intestine is
Answer
D. Bacteroides fragilis
43
Man is the intermediate host in
Answer
B. Echinococcus granulosus
44
The infective form of Entamoeba histolytica
Answer
D. Mature cyst
45
The causative agent of Kala-azar
Answer
A. Leishmania donovani
46
Advantage of a thick smear for diagnosis of malaria includes all, except
Answer
C. Easy species identification
47
The specimen for Onchocerca volvulus is best collected around
Answer
Question Cancelled
48
Which of the following is detected by salt floatation method?
Answer
Question Cancelled
49
All of the following are dimorphic fungi, except
Answer
C. Asergillus flavus
50
Which is the stain used for the demonstration of capsule of Cryptococcus neoformans?
Answer
Question Cancelled
51
The following is an example of Dermatophyte.
Answer
C. Epidermophyton species
52
The percentage of KOH used for skin scrapings and plucked hair samples
Answer
D. 10%
53
Which of the following is the culture technique used to study the intact morphology of fungus?
Answer
B. Slide culture
54
The fungus which is not cultivable
Answer
B. Pneumocystis jirovecii
55
Negri bodies are the characteristic of
Answer
D. Rabies
56
All of the following are enveloped viruses, EXCEPT
Answer
C. Polio Virus
57
Which among the following is a continuous cell line?
Answer
A. HeLa cell line
58
Primary viral infection may be diagnosed serologically by detection of
Answer
B. Virus specific IgM
59
Ideal temperature for storage of specimens for less than 5 days for viral diagnosis:
Answer
A. 4Β°C
60
Rota virus can be detected in stool by
Answer
D. All of the above
61
Which of the following statement is/are correct about new glassware? (i) It is alkaline in nature and should be soaked in dilute acid before use. (ii) It is acidic in nature and should be soaked in dilute alkali before use. (iii) It should be soaked in 5% hypochlorate solution before use.
Answer
B. Only i
62
Phenol belongs to which category of lab chemical?
Answer
Question Cancelled
63
What is the term for the mixture that remains in the distillation flask after the distillation of water?
Answer
B. Residue
64
Which of the following is a derived SI unit?
Answer
D. Pascal (Pa)
65
What is the formula to calculate Molarity?
Answer
Question Cancelled
66
For the estimation of urine steroid, which specimen is more preferable?
Answer
C. 24 hr urine sample
67
What is the key component of chromic acid cleaning solution?
Answer
B. Conc. H2SO4
68
What is the mechanism of action of heparin as an anticoagulant?
Answer
C. Enhancing antithrombin III activity
69
Which is the ideal urine preservative for bacterial culture?
Answer
D. Boric acid
70
Which of the following statements is/are correct? (i) Refrigeration of blood specimen leads to false high potassium level. (ii) Glycolysis can occur if fluoride–oxalate anticoagulant is not used. (iii) Haemolysed sample can be used to prepare a pooled sample.
Answer
B. Only i & ii
71
For Hba1C estimation, blood should be collected in
Answer
D. Purple colour coded vacutainer
72
Which of the following isotope is used to detect lifespan of RBC?
Answer
D. Chromium
73
Metabolic acidosis is characterised by
Answer
A. Decreased bicarbonate
74
High anion gap acidosis is not seen in
Answer
D. Renal tubular acidosis 69/2025 17
75
Pancreatic juice contains the following enzymes for lipid digestion, EXCEPT
Answer
A. Hormone sensitive lipase
76
Random blood sample is collected from a person
Answer
D. No such time interval is prescribed
77
Ketone body synthesis takes place mainly in
Answer
D. Liver
78
Which of the following molecules does not contain heme as a constituent?
Answer
D. Ferroxidase
79
All of the following are considered as trace elements, EXCEPT
Answer
C. Magnesium
80
The isoenzyme of creatine kinase elevated in myocardinal infarction is
Answer
A. CK-MB
81
Which among the following enzymes are activated on dephosphorylation process?
Answer
B. HMG – CoA reductase
82
Thyroid Stimulating Hormone (TSH) is measured after the administration of exogenous Thyrotropin Releasing Hormone (TRH) to assess the function of anterior pitutory gland. In this test, a delayed rise of TSH is seen in
Answer
C. Tertiary hypothyroidism
83
Which is not a characteristic of genetic code?
Answer
B. Overlapping
84
RNase H is used in
Answer
Question Cancelled
85
The cDNA is prepared using the enzyme
Answer
C. Reverse transcriptase
86
Colourless refractile hexagonal plate like crystals are found in urine due to
Answer
A. Cystine
87
Which is not a feature seen in CSF of patients with cryptococcosis?
Answer
Question Cancelled
88
Hypoacidity in stomach is seen in
Answer
B. Gastric carcinoma
89
Factors responsible for the formation of urinary stones are all, except
Answer
C. Hypoparathyroidism
90
Increased mobility of molecules in electrophoresis is seen in all conditions, except
Answer
A. High resistance of electric field
91
In which type of chromatography techniques, the larger molecules will come out first, while the smaller molecules are retained in the column?
Answer
B. Gel filtration chromatography
92
Common location reagents (locating agents) used for visualisation of chromatography are, i. Sulfuric Acid ii. Amido schwartz iii. Ninhydrin iv. Diphenylamine
Answer
D. i, iii and iv only
93
All are immunoassay techniques, except
Answer
B. Electrophoresis
94
Which is the predominant class of antibodies in primary immune response?
Answer
A. IgM
95
All are the markers of cholestasis, except
Answer
C. LDH
96
_____ is the fraction of those without the disease that the test correctly predicts.
Answer
B. Specificity
97
Which among the following is/are used as screening procedures for detection of drugs? (i) Ferric chloride Test (ii) Anion Gap (iii) ECG (iv) Chromatography
Answer
A. All of the above
98
Automated methods used for specimen delivery are (i) Pneumatic tube systems (ii) Electric track vehicles (iii) Courier Service (iv) Mobile robots
Answer
D. i, ii and iv only
99
______ is a substance having homogeneous and well-established values used for the calibration of an apparatus, an assay method or assigning values to materials.
Answer
B. Reference material
100
Elapsed time between two points on the laboratory's path of work through pre-examination, examination and post examination processes is known as
Answer
B. Turnaround Time

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