| Post Name | LABORATORY TECHNICIAN GR. II- IMS/HEALTH etc.. |
|---|---|
| Question Paper Code | 007/2022 |
| Category Code | 101/2019, 144/2021, 359/2020, 528/2019, 198/2021 |
| Date of Test | 28 January 2022 |
| Medium of Question | ENGLISH |
| Exam Type | OMR Examination |
| Total Questions | 100 |
1
In a case of Acute Lymphoblastic Leukemia, the lymphoblasts demonstrated strong
localized positivity with acid phosphatase.
The cells were positive for CD2 and CD7 and negative for CD19, CD24, and CD20.
These blasts are most likely :
Answer
B. T lymphoblasts
2
A patient with anemia of chronic disease is most likely to have which set of laboratory
test results ?
Answer
C. MCV normal, serum iron decreased, serum ferritin increased, TIBC and %
saturation decreased
3
An increase in the reticulocyte count is accompanied by :
Answer
C. Polychromasia on the Romanovsky stained blood smear
4
A 8-year-old boy presents with intramuscular hematomas and recurrent hemarthroses.
Laboratory tests reveal normal platelet count bleeding time, and PT, but the PTT is
prolonged. This condition most likely results from an abnormality involving :
Answer
D. X Chromosome
5
A patient is suspected of having hemolytic anemia. Numerous spherocytes are present
in the blood smear, and the reticulocyte count is 18%. What test should be done to
determine whether this is an autoimmune process ?
Answer
A. Direct Antiglobulin Test
6
A joint aspiration is performed on a 60 year old lady with painful swollen elbow, and a
sample is sent to the laboratory. A cytocentrifuged slide is examined with polarized
light shows needlelike intracellular and extracellular crystals which exhibit negative
birefringence compensator. These crystals would be best identified as which of the
following ?
Answer
C. Monosodium urate
7
A thoracentesis is performed on a large pleural effusion yielded 1.2 L of thick, yellow
fluid. Laboratory studies show a total protein of 4.5 g/dL (serum=6 g/dL) lactate
dehydrogenase 40 U/L (serum = 50 u/L) and total leukocyte count of 20,000/microlitre
with 90% segmented neutrophils. Which statement fits most well for this fluid ?
Answer
A. This is an exudate
8
Hematuria with dysmorphic RBCs is a hallmark of :
Answer
B. Acute Glomerulonephritis
9
Microalbuminuria is defined as level of albumin in urine at range of :
Answer
C. 30-300 mg/day
10
A 51-year-old man is admitted following an episode of hematemesis in which he
remembers vomiting about a liter of dark red bloody vomitus into the. He is found to
have orthostatic hypotension. His Hgb is 6.2 g/dL, Hct 18.8%, MCV 74 fL, platelet
count 90,000/uL, and WBC count 10,100/uL. His prothrombin time is 12.1 seconds and
partial thromboplastin time 26.2 seconds. Which of the following blood products is
most appropriate for this man ?
Answer
D. Packed RBC’s
11
A recipient developed a sudden drop in blood pressure following transfusion, though
he remained afebrile. Which of the following conditions is most likely to be found ?
Answer
D. IgA deficiency
12
One unit of FRESH FROZEN PLASMA prepared from whole blood contains
__________ ml of plasma.
Answer
C. 200-250
13
Coombs control cell consists of :
Answer
A. Type O positive cells coated with Anti D
14
Nucleic acid Amplification Test for HIV was instituted in donor testing protocols to :
Answer
C. Reduce window period to detect virus earlier than other available tests
15
Gauge of needle ideal for blood transfusion generally is :
Answer
C. 16 G
16
Which of the following is an example of Iron Hematoxylin ?
Answer
C. Weigerts Hematoxylin
17
Which of the following microtome is better for cutting large specimens for museum ?
Answer
C. Sledge microtome
18
Which of the following is a routinely used clearing agent in histopathology ?
Answer
B. Xylene
19
Which of the following is not a slide adhesive ?
Answer
A. DPX
20
Which of the following is not an aqueous mounting media ?
Answer
D. Canada balsam
21
Which among the following is the best stain for demonstration of Barr Body ?
Answer
B. Orcein stain
22
Which of the following EA (Eosin Azure) is preferred for non-gynaecological smears ?
Answer
C. EA 65
23
Which of the following fixative is not useful in a Millipore Filter (membrane filter) ?
Answer
C. 100% Methanol
24
Which among the following is the most suitable fixative for gastric washings ?
Answer
C. 95% Ethanol
25
Carnoy’s fixative do not contain __________.
Answer
D. Formaldehyde
26
Tissue of choice for routine karyotyping :
Answer
A. Blood
27
Anticoagulant of choice for chromosome analysis like Karyotyping :
Answer
B. Heparin
28
Which type of chromosome abnormality is characteristically seen in Philadelphia
chromosome ?
Answer
C. Translocation
29
Which is the standard/Routine banding technique used in chromosome studies ?
Answer
D. G-Banding
30
Which of the following techniques can be used in diagnosing haematological
malignancy ?
Answer
D. All the above
31
Sterilisation techniques are first developed by :
Answer
D. Louis Pasteur
32
The microscope which is used to visualize organisms which are live and unstained :
Answer
B. Dark field microscope
33
Holding period of Laboratory Autoclave :
Answer
C. 121ďż˝ for 15 minutes, 15 lbs
34
Which of the following statement is false about receiving clinical specimens in
laboratory ?
Answer
C. Unlabelled specimens and wrongly labelled specimens can be accepted
35
Which statement is false regarding ionising radiation ?
Answer
A. It has got a low penetrating power
36
All of the following tests are used for detecting efficacy of disinfectants except :
Answer
D. Serenys test
37
Isospora belong to which Sub-phylum ?
Answer
A. Sub-phylum Sporozoa
38
All the following helminthic eggs are not bile stained except :
Answer
C. Ascaris lumbricoides
39
NIH swabs are used for collecting specimens in suspected cases of :
Answer
D. Enterobiasis
40
Cryptosporidia oocysts are better stained and visualized by :
Answer
B. Modified acid fast staining
41
Which of the following is included in the laboratory diagnosis of Filariasis ?
Answer
D. All of the above
42
The major complication of Falciparum malaria :
Answer
D. All of the above
43
Which of the following statement about bacterial capsule is incorrect ?
Answer
D. Helps in bacterial motility
A 7 007/2022
{P.T.O.}
44
Which is the surrogate marker for detection of methicillin resistance mediated by
mec A gene in Staphylococcus Aureus by disc diffusion method ?
Answer
B. Cefoxitin
45
All are correct about autoclave except :
Answer
C. Spores of Bacillus Atrophaeus is used as sterilization control
46
Which of the following is a selective medium for Salmonella Typhi ?
Answer
A. Xylose lysine deoxycholate agar
47
Which is not correct regarding oxidase test ?
Answer
B. The test is performed on bacterial colonies from MacConkey’s agar
48
Which of the following can be used to stain metachromatic granules of Corynebacterium
diphtheriae ?
Answer
D. All of the above
49
Which of the following cannot be cultivated in artificial culture media ?
Answer
B. Rhinosporidium seebri
50
All are true about Sabouraud’s dextrose agar except :
Answer
A. pH of the medium is 8.6
51
Which of the following is/are true of dimorphic fungi ?
Answer
D. All of the above
007/2022 8 A
52
Candida albicans shows the following characteristics except :
Answer
A. Is a true yeast
53
Which of the following fungi causing human disease is not a common laboratory
contaminant ?
Answer
B. Cryptococcus spp
54
Which of the following statement regarding dermatophytes is not correct ?
Answer
C. Sensitive to cycloheximide
55
An example of continuous cell line for virus isolation is :
Answer
A. Human carcinoma of cervix cell line
56
In a patient with chronic hepatitis B virus infection which serological marker indicates
high infectivity ?
Answer
B. Hepatitis B (Precore) antigen
57
All of the following are true of viral inclusion bodies except :
Answer
B. They are situated only in the cytoplasm of infected cells
58
Which of the following is not correct regarding biosafety cabinets ?
Answer
A. Biosafety cabinets are of 2 classes
59
Which of the following statements regarding prions is incorrect ?
Answer
B. They can be inactivated by boiling at 100�C
60
All of the following are true of NIPAH virus except :
Answer
C. It is a Biosafety level 2 pathogen
61
Among the following methods, identify the correct way of cleaning laboratory
glassware.
Answer
D. Soap water ďż˝ Tap water ďż˝ Deionized water ďż˝ Air drying
62
Identify the factor that is not a contributor in loss of pipetting accuracy.
Answer
C. Fluid volume 50% above minimum volume.
63
Out of the listed safety protocols, identify the protocol not adhering to proper laboratory
safety standard.
Answer
D. Used needles and blades should be safely disposed by wrapping in paper towels.
64
In a chemical laboratory, identify the protocol not adhering to proper chemical storage
standards.
Answer
B. Oxidizers and flammables should be stored in same cabinet for easy access.
65
Highest purity of water is indicated by which conductivity ?
Answer
A. 18.2 M٠cm��
66
Identify the SI unit of temperature.
Answer
C. Kelvin
67
Molarity is defined as __________ of a substance __________ one litre of distilled water.
Answer
D. Gram molecular weight, Dissolved and made upto
68
Safe disposal of biological specimen should be ensured by which of the following ?
Answer
B. Specimen should be placed in an autoclave bag and autoclaved for 1 hour.
69
Identify the most appropriate anticoagulant for use in blood banking.
Answer
A. Citrate Phosphate Dextrose/Acid Citrate Dextrose
70
Urine specimen preservation is achieved with which of these chemicals ?
Answer
D. Boric acid
71
Flame photometer is based on characteristic emission by metals when __________.
Answer
B. Given sufficient energy in the form of heat.
72
Radioactive emission of a liquid specimen can be accurately quantified by which of the
following methods ?
Answer
D. Scintillation counter
73
From the buffer systems listed below, identify the buffer most important in maintaining
blood pH.
Answer
A. Carbonic acid-bicarbonate buffer
74
Tyndall effect is displayed by __________ when a beam of light is passed through it.
Answer
B. Colloids
75
In column chromatography, isocratic elution refers to :
Answer
D. Solvent system with constant polarity
76
Separation of amino acids by Silica gel thin layer chromatography is based on :
Answer
C. Interaction of R-group of amino acids with stationary phase
77
Among the following, identify a protocol not complying with good practices in a clinical
biochemistry laboratory.
Answer
A. Protocols can be amended by the personnel at their discretion.
78
What is not an advantage of an autoanalyzer in a clinical laboratory ?
Answer
D. None of these.
79
Identify the main benefit of adopting laboratory informatics in a clinical laboratory.
Answer
C. Databases help in result recording, retrieval, and analysis.
80
Analytical variables can arise from which of the following factors ?
Answer
D. All of these.
007/2022 12 A
81
The specific site of action of trypsin is :
Answer
A. Peptide bond formed by Carboxyl groups of basic amino acids.
82
Soret band is observed at :
Answer
D. 400 nm
83
Enzyme defect in acute intermittent porphyria :
Answer
B. PBG deaminase
84
Which among the following enzymes is an indicator of vitamin Bďż˝ deficiency ?
Answer
A. Erythrocyte transketolase
85
Which among the following is true for competitive enzyme inhibition ?
Answer
D. Km increases, Vmax is constant
86
The De Ritis ratio > 2 is seen in :
Answer
C. Alcoholic hepatitis
87
The isoenzyme of alkaline phosphatase that is heat stable is found in :
Answer
D. Placenta
88
Low TSH levels with low radioactive iodine uptake is characteristic of :
Answer
D. Postpartum thyroiditis
89
Which of the following is not true about Taq polymerase used in PCR ?
Answer
A. 3’-5’ polymerase activity
90
Genetic code is all except :
Answer
B. Non-universal
91
About plasmids all are true except :
Answer
D. They replicate with bacterial DNA replication
A 13 007/2022
{P.T.O.}
92
Regarding urinary 5-HIAA which among the following is true ?
Answer
A. Acidic urine preservatives should be used
93
Regarding CSF glucose which is correct ?
Answer
A. Normal CSF glucose is 60-70% of blood glucose
94
In pentagastrin test, high acid secretion is observed in :
Answer
B. ZE syndrome
95
Staghorn urinary calculus is formed by :
Answer
A. Phosphate stones
96
In SDS PAGE electrophoresis :
Answer
A. The proteins move towards anode
97
In which type of ELISA is the absorbance inversely related with antigen
concentration ?
Answer
C. Competitive ELISA
98
The immunoglobulin increased in secondary response is :
Answer
B. IgG
99
The cardiac biomarker that can be used to diagnose heart failure :
Answer
C. BNP
100
The confirmatory method for identification of drugs of abuse is :
Answer
B. Gas chromatography/mass spectrometry
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