| Post Name | SENIOR LECTURER IN RADIOTHERAPY NCA- MEDICAL EDUCATION |
|---|---|
| Question Paper Code | 103/2017/OL |
| Category Code | 155/2017 |
| Date of Test | 9 January 2018 |
| Medium of Question | ENGLISH |
| Exam Type | Online Examination |
| Total Questions | 100 |
1
The most important soil found in the Chittur Taluk of Palakkad district
Answer
B. Black soil
2
The Father of the Modern Kerala Renaissance
Answer
C. Sree Narayana Guru
3
The Indian metropolitan city that locate nearest to equator
Answer
A. Chennai
4
The Government of India decided to observe Rashtriya Ekata Diwas on
Answer
D. October 31
5
The largest reservoir in Kerala
Answer
A. Malampuzha
6
The famous Kallumala Samavam was known as
Answer
C. Perinattu Lehala
7
The First Women Chief Justice of a High Court
Answer
B. Leila Seth
8
The Northern part of the west coastal plain is known as
Answer
D. Konkan Coast
9
The largest river basin in India
Answer
B. Ganges
10
The spice garden of Kerala
Answer
A. Idukki
11
The first E-port in India
Answer
D. Kochi
12
The Ananda Mahasabha was founded by
Answer
C. Brahmananda Swami Sivayogi
13
Who was the president of K. P. C. C. during the time of India's Independence ?
Answer
A. K. Kelappan
14
The NITI Aayog came into force on
Answer
B. 2015 January 1
15
The agency to calculate the National of India
Answer
D. C. S. O.
16
Who is considered as the Patriotic Saint of India
Answer
A. Swami Vivekananda
17
The Socrates of Maharashtra
Answer
C. Gopalakrishna Gokhalea
18
The main disciple of Vaikunda Swamikal
Answer
C. Thycaud Ayya
19
The longest east flowing river of Kerala
Answer
B. Kabani
20
The winner of Australian Open tennis 2016
Answer
D. Rojer Federer
21
As per RTOG 0933 dosage guideline, the constraint for the hippocampus is:
Answer
A. D100% ≤ 9 Gy, maximum dose ≤ 16 Gy
22
Which is NOT an advantage with regard to hyperfractionation ?
Answer
B. Destroys more tumor cells
23
Unit if NSD expression
Answer
B. Ret
24
Alpha by beta experimental value of testis is
Answer
B. 12-13
25
Majority of tumour cells have a diameter of
Answer
B. 20-30 micrometer
26
With regard to molecular basis of blood vessel branching in tumour angiogenesis which is not a correct match with regard to the key molecular player involved in it
Answer
D. Stalk elongation-ANG-2
27
S.I unit of radiation exposure
Answer
D. None of the above
28
In gamma knife, the unit centre point is how much distance away from each Co⁶⁰ source?
Answer
B. 40 cm
29
Which is false with regard to 6MV photon beam ?
Answer
B. 10 cm PDD = 61%
30
With regard to composition of Lipowitz metal which is wrong
Answer
C. 3+6.7% lead
31
With regard to radiation treatment of patients with cardiac pacemakers which is wrong
Answer
C. Before treatment, estimate and record the dose (from scatter) to be received by the pacemaker. The total accumulated dose should not exceed approximately 1 Gy
32
With respect to interaction of electron beam with bone which is false ?
Answer
B. Dose outside (inside) the bone-water interface increases (decreases) by approximately 15% as a result of loss of side scatter equilibrium
33
Which statement about a hot spot as per ICRU Report 62 is wrong?
Answer
D. At least 2 cm² in a section
34
The difference between the volume enclosed by the external contour of the patient and that of the CTVs and OARs on the slice that have been imaged is
Answer
D. None of the above
35
Which of the following is not correct for Rando phantoms?
Answer
B. The phantom is made of human tissue-equivalent materials to work with only for x-rays
36
What is the flexure dose ?
Answer
A. Alpha/beta × 0.1
37
Which of the following match-ups is not correct concerning tissue and organ response to radiation ?
Answer
A. Michalowski-flexible vs. hierarchical and alpha by beta ratio
38
Which of the following statements is not correct concerning synovial sarcoma ?
Answer
B. More than 50% of cases are seen in the upper extremities
39
Which of the following is not correct for anal canal anatomy ?
Answer
D. The epithelium proximal to the dentate line is a special non-keratinized squamous epithelium with no hair follicles or sweat glands, also called the anoderm
40
Which of the following studies demonstrated the detrimental effect of post-operative radiotherapy on survival of patients with pancreatic cancer ?
Answer
A. ESPAC-1, 2001
41
65 year old female presented with vulvar pruritus and a lump in the left groin for further evaluation in gynecology. During the gynecological examination, a fixed 1×1 cm left groin lymphadenopathy was detected as well as a mobile 1×1.5 cm vulvar lesion at the labia minora. In her pelvic MRI, the labia minora lesion was 1.2×1.9 cm without extension to the lower urethra and the lower third of the vagina or anus, in addition to no gross lymphadenopathy except a left inguinal single lumphadenopathy measuring 1×1.5 cm in size. PET CT workup defined the tumor in the vulva and a left-sided single inguinal node without distant metastasis. The biopsy of the vulvar lesion revealed squamous cell carcinoma. What is her FIGO staging ?
Answer
D. Stage IIIA
42
The estimated risk of sub-clinical cervical lymph node metastasis is between 20-30% for all the following EXCEPT
Answer
D. T2 supra-glottic larynx
43
Which of the following do not belong to papillary variant of thyroid cancer classification ?
Answer
A. Insular variant
44
Which among the following is false with respect of HPV in oropharyngeal cancer ?
Answer
D. HPV-associated oropharyngeal cancers are characterized frequently as well differentiated non-keratinizing or basaloid in histopathology
45
In the conventional radiation treatment of hypopharyngeal cancers the anatomical field borders given below are usually followed EXCEPT
Answer
B. Posterior-in front of vertebral spinous processes
46
Which of the following is not correct for laryngeal cancers ?
Answer
B. Synchronous carcinoma incidence in a patient with laryngeal cancer is approximately 15%
47
Which of the following is not correct for oral cavity malignancies ?
Answer
D. When clinical N(-) tongue cancers are examined histopathologically, pathological lymph node positively is nearly 19%
48
Which of the following is not correct for esthesioneuroblastoma ?
Answer
D. Most patients are in early stages at presentation
49
Which one of the following lung cancers is more strongly associated with smoking ?
Answer
A. Small cell lung cancer
50
What is the extensive in-situ component in invasive ductal cancer of breast ?
Answer
C. 25%
51
Which of the following should be known to calculate lymph node metastasis risk according to Roach formulas ?
Answer
C. PSA level-Gleason score
52
Where is the H point ?
Answer
A. The tips of ovoids are connected with a horizontal line and 2 cm superior and 2 cm lateral from the middle of this line are the H points on the right and left sides
53
Which of the following STSs has a high potential for distant metastasis ?
Answer
D. Rhabdomyosarcoma
54
Which of the following statements is not correct for Merkel cell carcinoma ?
Answer
D. Lymphatic involvement is less than 5%
55
Which of the following margin matches is not correct for radiotherapeutic planning for skin cancer ?
Answer
C. Tm > 3 cm SCC : 3 cm
56
What is the optimal total radiation dose required for immunosuppression and tumoral cell eradication in fractionated TBI regimes ?
Answer
D. 8-12 Gy
57
A 7 year old boy was admitted to the emergency with severe headaches, nausea, and vomiting. His examination revealed decreased upward gaze in addition to inability to focus on objects and double vision. There was abnormal light response during accommodation. He had an MRI demonstrating hydrocephalus with a pineal region mass obstructing the aqueduct of Sylvius. What syndrome is this ?
Answer
A. Parinaud syndrome
58
A 4-year-old boy was brought to the attention of an ophthalmologist because of strabismus and right-sided leukocoria. He was clinically diagnosed as having retinoblastoma and the intraocular mass workup revealed a 13-mm diameter and 11-mm thick tumor with vitreous seeding, as well as sub-retinal seeding more than 4 mm from the tumor. The tumor did not touch the lens and did not involve anterior segment structures such as the ciliary body. He had no neo-vascular glaucoma or opaque media from hemorrhage. His tumor has only caused a minor loss of vision. Which is false?
Answer
A. The international classification for intraocular retinoblastoma in this case is "C"
59
45-year-old woman with a long history of hyperthyroiditis presents with eyelid retraction, exophthalmos, diplopia and periorbital edema. In her history of illness, she specifically notes that she has had deterioration in her vision over the last 10 days accompanied by diplopia 1 day ago. She has not experienced any loss of color vision or demonstrated corneal involvement, but she has minor visual field defects with blurred vision. She is diagnosed with Graves' disease and thyroid ophthalmopathy. Which of the statement is false ?
Answer
B. With radiotherapy there is improvement in proptosis, eyelid retraction , or soft tissued chnages which has not been clearly defined
60
38 years old male with complaints of non-specific headaches for almost 6 months has been evaluated by neurology. His brain MRI has demonstrated a recent bleeding and a dark flow void surrounding the nidus of an arteriovenous malformation in the thalamus, which was 1.5 cm in size. The angiography confirmed this diagnosis in addition to showing no deep venous drainage. He currently has no neurological symptoms. What is the rough risk of bleeding in his lifetime ?
Answer
C. 67%
61
45 years old male presents for a hip reconstruction operation after a blunt trauma to his femoral prosthesis. In his workup,radiology demonstrated bone spurs from the proximal femur in addition to a ≥ 1 cm gap between the opposing surfaces. The surgeon asks your opinion about prophylaxis of heterotropic ossification in order to choose between a medical or radiotherapy approach. Which is incorrect statement ?
Answer
B. Radiotherapy is approximately thrice as effective as non-steroidal anti-inflammatory medications
62
52 years old female has been sent to radiation oncology to be evaluated for keloid prophylaxis following planned forearm surgery because of her keloid scar experience after a cesarean section. Which is correct statement ?
Answer
A. There is currently no real standard. However, experience with post-operative radio therapy is well documented
63
Fifty eight year old female has status post-total gastrectomy with stage llla gastric cancer with pT4aN1M0 gastric adenocarcinoma. Which statement is false ?
Answer
B. Dihydro Pyrimidine Dehydrogenase deficiency (DPD deficiency) an autosomal dominant metabolic disorder may be suspected when the patient has very severe life-threatening toxicity after one cycle of chemotherapy
64
A fine-needle aspiration of the head of the pancreas revealed adenocarcinoma. Based on his imaging studies, he was found to have a 2.5×3.2×2.3 cm uncinate mass in the pancreas, which was encasing the superior mesenteric artery by approximately 180°. The mass is separate from the celiac axis and portal vein and the SMV abuts the mass for less than 90° of its circumference. There appear to be a few lymph nodes in the vicinity workup revealed no distant metastasis. This disease is
Answer
C. Borderline resectable
65
Which is adverse cytogenetics in AML ?
Answer
A. t(9:22) (q34:q11)
66
With respect to CNS prophylaxis in acute lymphoblastic leukemia is true ?
Answer
D. All are true
67
In staging of lymphoma the use of A or B is based on the absence or presence of three symptoms respectively. What does "A" stand for ?
Answer
D. None of the above
68
As per GHSG which among the following is not included in the risk factor for Hodgkin lymphoma ?
Answer
C. Age ≥50 yrs.
69
Which is not correct match with regard to international prognostic score for advanced Hodgkin lymphoma ?
Answer
C. Number of risk factors 4.7-5 yrs. OS 49%
70
Which infection is not "significant to high" risk in allogeneic stem cell transplant ?
Answer
C. Candida
71
Antidote for vinblastine extravasation is
Answer
D. Hyaluronidase
72
In chemotherapy extravasation cold compresses are given except in
Answer
D. Cabazitaxel
73
In the escalated BEACOPP schedule, the dose of prednisolone is:
Answer
A. 40 mg/m²/day PO
74
Which match is wrong with regard to the common diagnostic profile ?
Answer
D. CLL-CD3
75
Minimum platelet counts required and the intervention which is not correct ?
Answer
A. Lumbar puncture - 50,000/L
76
What is the half-life of infused coagulation factors V, VII, VIII and protein C in FFP ?
Answer
A. <12 hours
77
Wells criteria is a prediction tool in
Answer
A. DVT
78
Clostridium difficle associated diarrhea which is false ?
Answer
D. Clostridium difficle toxins A/B in stool is not usually sufficient for diagnosis
79
MASCC scoring index in febrile neutropenia. Which is incorrect score ?
Answer
C. No hypotension-4
80
Which is not an equi-analgesic dose ?
Answer
D. 8 mg SR hydromorphone
81
Which is incorrect with regard to the use of Low Molecular Weight Heparin (LMWH) for treatment of thromboembolism ?
Answer
B. Dalteprin 200U/kg twice daily
82
Regarding antineoplastic drugs and incidence of left ventricular dysfunction, which is an incorrect match?
Answer
A. Doxorubicin 400 mg/m² — 7 to 26%
83
Damocles syndrome is usually seen in
Answer
A. Cancer survivors
84
As per ASTRO consensus patient not ideal for APBI off trial
Answer
D. Pure DCIS ≤3 cm in size
85
Which is considered highest risk site in squamous cell carcinoma ?
Answer
A. Ear
86
What is the pain score to start step 3 analgesics ?
Answer
A. >6
87
Which of the following is the most frequent metastatic region in pancreatic cancer ?
Answer
B. Peritoneum-liver
88
Who was the founder director of Regional Cancer Center, Trivandrum ?
Answer
A. M. Krishnan Nair
89
A 69-year-old patient presents with weight loss of 10 kg, fatigue and abdominal pain. Investigations show a mass in the right colon, widespread liver metastases and 3 lung nodules. Investigations show Hb 110 g/L, WCC 8 × 10⁹/L, alkaline phosphatase 562 U/L, albumin 25. He is unable to continue with his hobby of woodwork but otherwise is self-caring. Which of the following would influence his management?
Answer
C. His albumin level, alkaline phosphatase and age
90
STAR trial was for which malignancy ?
Answer
A. Renal cell carcinoma
91
In COMBARZ trial, the drugs compared were
Answer
B. Sunitinib vs Pazopanib
92
Risk of malignancy index incorporates all EXCEPT
Answer
D. Age
93
With regard to the traffic light system in the use of Trastuzumb which is wrong
Answer
C. A red light indicates LVEF ≤0.40 and symptoms and signs of cardiac failure
94
Which is not a correct match ?
Answer
D. CK20-Endometrial cancer
95
In which of the following tumors does survival increase with increasing age ?
Answer
D. Brainstem glioma
96
Deletion of 1p and 19q in oligodendroglioma is associated with
Answer
D. Better response to therapy with improved progression-free and overall survival
97
All of the following are true regarding the etiology of melanoma, except
Answer
C. Half of those with melanoma possess the CDKN2A mutation
98
GORTEC 94-01 demonstrated a benefit to concurrent chemoradiation over radiation alone in advanced oropharynx cancer in terms of
Answer
B. Local control and overall survival benefit
99
According to a meta-analysis by Fried et al. regarding the timing of thoracic radiotherapy in addition to chemotherapy, which of the following constituents "early" thoracic radiotherapy ?
Answer
C. Beginning within 9 weeks of starting chemotherapy
100
Which among the following is incorrect with regard to the government schemes for cancer and other patients?
Answer
B. RSBY-CHIS PLUS is a Central Government scheme
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